Visible-Light Decatungstate/Disulfide Dual Catalysis for the Hydro-Functionalization of Styrenes

Alexis Prieto (1) , Marc Taillefer (1)

1 ICGM - Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier

We describe an efficient photoredox system, relying on decatungstate/disulfide catalysts, for the hydrofunctionalization of styrenes. In this methodology the use of disulfide as co-catalyst was shown to be crucial for the reaction efficiency. This photoredox system was employed for the hydro-carbamoylation,-acylation,-alkylation and-silylation of styrenes, giving access to a large variety of useful building blocks and high-value molecules such as amides and unsymmetrical ketones from simple starting materials.

Mots clés: Radicals; Photocatalysis; Dual catalysis; Hydrofunctionalization

Domaines: Chimie; Chimie organique

Alexis Prieto, Marc Taillefer. Visible-Light Decatungstate/Disulfide Dual Catalysis for the Hydro-Functionalization of Styrenes. Organic Letters, 2021, 23, pp.1484-1488. ⟨10.1021/acs.orglett.1c00189⟩. ⟨hal-03132428⟩