The Usefulness of Trivalent Phosphorus for the Synthesis of Dendrimers - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Molecules Année : 2021

The Usefulness of Trivalent Phosphorus for the Synthesis of Dendrimers

Résumé

Dendrimers are hyperbranched macromolecules, which are synthesized step-by-step by the repetition of a series of reactions. While many different types of dendrimers are known, this review focusses on the use of trivalent phosphorus derivatives (essentially phosphines and phosphoramidites) for the synthesis of dendrimers. The first part presents dendrimers constituted of phosphines at each branching point. The other parts display the use of trivalent phosphorus derivatives during the synthesis of dendrimers. Different types of reactions have been applied to phosphines. The very first examples of phosphorus-containing dendrimers were obtained by the alkylation of phosphines. Then, several families of dendrimers were elaborated by reaction of phosphoramidites. Such a type of reaction is the base of the solid phase synthesis of oligonucleotides; it has been applied in particular for the synthesis of dendrimers constituted of oligonucleotides. Finally, the Staudinger reaction between phosphines and azides afforded different families of dendrimers, and was at the origin of accelerated methods of synthesis of dendrimers. Besides, the reactivity of the P=N-P=S linkages created by this reaction led to very original dendritic structures.
Fichier principal
Vignette du fichier
Molecules 2021, 26, 269..pdf (15.64 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03131217 , version 1 (04-02-2021)

Identifiants

Citer

Anne-Marie Caminade, Kathleen Moineau-Chane Ching, Béatrice Delavaux-Nicot. The Usefulness of Trivalent Phosphorus for the Synthesis of Dendrimers. Molecules, 2021, 26 (2), pp.269. ⟨10.3390/molecules26020269⟩. ⟨hal-03131217⟩
56 Consultations
14 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More