Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine

Giulia r. Fois , Frank j. Meye , Christelle Glangetas , Giulia R Fois , Marion Jalabert , Salvatore Lecca , Kristina Valentinova , Frank J Meye , Marco A. Diana , Philippe Faure , Manuel Mameli , Stéphanie Caille , F Georges (1)

1 IINS - Interdisciplinary Institute for Neuroscience [Bordeaux]

Highlights d vSUB controls the phasic activity of VTA dopamine neurons d The BNST relays the excitatory drive from the vSUB to VTA dopamine neurons d vSUB stimulation promotes persistent hyperactivity of VTA dopamine neurons d vSUB-driven NMDA-LTP in the BNST gates cocaine-induced locomotor activity

Domaines: Sciences du Vivant [q-bio]

Giulia r. Fois, Frank j. Meye, Christelle Glangetas, Giulia R Fois, Marion Jalabert, et al.. Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine. Cell Reports, 2015, 13 (10), pp.2287 - 2296. ⟨10.1016/j.celrep.2015.10.076⟩. ⟨hal-03130806⟩