Mucoadhesive microgel compositions and methods for using the same
Résumé
Mucoadhesive microgel compns., which include an active agent (such as HB-EGF), are provided. Aspects of the invention include a microgel comprising a crosslinked poly(ethylene glycol) Me ether methacrylate polymer comprising a mucoadhesive functionality. Also provided are methods of making and using the mucoadhesive microgel compns., e.g., in therapeutic applications. In one embodiment, HB-EGF loaded mucoadhesive microgel compns. are provided, e.g., for prevention or treatment of mucositis conditions, such as therapy induced oral mucositis conditions.