Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys

Marco K Wittmann , Elsa Fouragnan , Davide Folloni , Miriam C Klein-Flügge , Bolton K H Chau , Mehdi Khamassi (1) , Matthew F S Rushworth (2)

1 ISIR - Institut des Systèmes Intelligents et de Robotique
2 Department of Experimental Psychology, University of Oxford, Oxford, UK

People and other animals learn the values of choices by observing the contingencies between them and their outcomes. However, decisions are not guided by choice-linked reward associations alone; macaques also maintain a memory of the general, average reward ratethe global reward statein an environment. Remarkably, global reward state affects the way that each choice outcome is valued and influences future decisions so that the impact of both choice success and failure is different in rich and poor environments. Successful choices are more likely to be repeated but this is especially the case in rich environments. Unsuccessful choices are more likely to be abandoned but this is especially likely in poor environments. Functional magnetic resonance imaging (fMRI) revealed two distinct patterns of activity, one in anterior insula and one in the dorsal raphe nucleus, that track global reward state as well as specific outcome events.

Domaines: Neurosciences [q-bio.NC]; Robotique [cs.RO]; Intelligence artificielle [cs.AI]; Psychologie; Sciences cognitives

Marco K Wittmann, Elsa Fouragnan, Davide Folloni, Miriam C Klein-Flügge, Bolton K H Chau, et al.. Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys. Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-17343-w⟩. ⟨hal-03098645⟩