Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates

Maxime Bessières (1) , Vincent Hervin , Vincent Roy , Agnes Chartier (2) , Robert Snoeck (3) , Graciela Andrei (3) , Jean-François Lohier (1) , Luigi Agrofoglio (2)

1 LCMT - Laboratoire de chimie moléculaire et thioorganique
2 ICOA - Institut de Chimie Organique et Analytique
3 Rega Institute for Medical Research [Leuven, België]

Domaines: Chimie organique

Maxime Bessières, Vincent Hervin, Vincent Roy, Agnes Chartier, Robert Snoeck, et al.. Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates. European Journal of Medicinal Chemistry, 2018, 146, pp.678-686. ⟨10.1016/j.ejmech.2018.01.086⟩. ⟨hal-03090373⟩