Rapid Evolution of HERC6 and Duplication of a Chimeric HERC5/6 Gene in Rodents and Bats Suggest an Overlooked Role of HERCs in Mammalian Immunity

Stéphanie Jacquet (1, 2) , Dominique Pontier , Lucie Etienne (1)

1 LP2L - Interaction hôte pathogène lors de l'infection lentivirale – Host-Pathogen Interaction during Lentiviral Infection
2 LBBE - Laboratoire de Biométrie et Biologie Evolutive - UMR 5558

Mots clés: HERC; restriction factor; antiviral immunity; gene duplication; genetic conflicts; positive selection; HERC5; HERC6

Domaines: Sciences du Vivant [q-bio]

Stéphanie Jacquet, Dominique Pontier, Lucie Etienne. Rapid Evolution of HERC6 and Duplication of a Chimeric HERC5/6 Gene in Rodents and Bats Suggest an Overlooked Role of HERCs in Mammalian Immunity. Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.605270⟩. ⟨hal-03086365⟩