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Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity

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https://hal.archives-ouvertes.fr/hal-03052056
Contributor : Gilles Hanquet <>
Submitted on : Thursday, December 10, 2020 - 2:27:15 PM
Last modification on : Friday, December 11, 2020 - 3:35:28 AM

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Gilles Hanquet, Matúš Hlaváč, Lucia Kováčiková, Marta Šoltésová Prnová, Peter Šramel, et al.. Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity. Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (1), pp.369-381. ⟨10.1021/acs.jmedchem.9b01747⟩. ⟨hal-03052056⟩

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