Recent achievements in copper catalysis for C-N bonds formation

Alexei D Averin (1) , Anton S Abel (1) , Olga K Grigorova (1) , Gennadij V Latyshev (1) , Yury N Kotovshchikov (1) , Alexander Yu Mitrofanov (1) , Alla G. Bessmertnykh-Lemeune (2) , Irina P Beletskaya (1)

1 Department of Chemistry, Lomonosov Moscow State University
2 LC - Laboratoire de Chimie - UMR5182

A mini-review describes the development of the catalysis by Cu(I) complexes aimed at the formation of C-N bonds at the Lomonosov MSU during 2010s. The main approach employs the amination of aryl and heteroaryl halides with the amines and polyamines, in this direction a great versatility of starting compounds was achieved: adamantanecontaining amines, linear diamines, oxadiamines and polyamines, various aryl iodides and bromides, derivatives of pyridine and quinoline were used for this purpose. In more peculiar cases, the copper catalysis was used for steroids transformations, including vinylation of azoles, widespread "click" reactions for the conjugate syntheses, and successful heterogenezation of the copper catalysts were also undertaken.

Mots clés: Cu catalysis; amination; polyamines; adamantane; click reactions; steroids; immobilization

Domaines: Chimie

Alexei D Averin, Anton S Abel, Olga K Grigorova, Gennadij V Latyshev, Yury N Kotovshchikov, et al.. Recent achievements in copper catalysis for C-N bonds formation. Pure and Applied Chemistry, inPress, ⟨10.1515/pac-2020-0301⟩. ⟨hal-03037715⟩