Preparation of perfluorocarbon emulsions by premix membrane emulsification for Acoustic Droplet Vaporization (ADV) in biomedical applications

Romain Melich (1) , Ali Zorgani , Frédéric Padilla , Catherine Charcosset (1)

1 UCBL - Université Claude Bernard Lyon 1

Perfluorocarbon (PFC) droplets are used in acoustic droplet vaporization (ADV), a phenomenon where droplets vaporize into gas microbubbles under exposure to ultrasound. The size and the size distribution of a phase change contrast agent is an important factor in determining the ADV threshold and the biodistribution.

Domaines: Sciences du Vivant [q-bio]; Sciences pharmaceutiques; Sciences de l'ingénieur [physics]; Génie des procédés

Romain Melich, Ali Zorgani, Frédéric Padilla, Catherine Charcosset. Preparation of perfluorocarbon emulsions by premix membrane emulsification for Acoustic Droplet Vaporization (ADV) in biomedical applications. Biomedical Microdevices, 2020, 22 (3), ⟨10.1007/s10544-020-00504-5⟩. ⟨hal-03028857⟩