White matter correlates of hemi-face dominance in happy and sad expression

Stefano Ioannucci (1) , Nathalie George (2, 3) , Patrick Friedrich (4) , Leonardo Cerliani (5) , Michel Thiebaut de Schotten (4)

1 INCIA - Institut de Neurosciences cognitives et intégratives d'Aquitaine
2 ICM - Institut du Cerveau = Paris Brain Institute
3 CENIR - Plateforme de neuroimagerie CENIR = Center for NeuroImaging Research-Human MRI Neuroimaging core facility for clinical research [ICM Paris]
4 IMN - Institut des Maladies Neurodégénératives [Bordeaux]
5 UvA - Universiteit van Amsterdam

The neural underpinnings of human emotional expression are thought to be unevenly distributed among the two brain hemispheres. However, little is known on the anatomy supporting this claim, particularly in the cerebral white matter. Here, we explored the relationship between hemi-face dominance in emotional expression and cerebral white matter asymmetries in 33 healthy participants. Measures of emotional expression were derived from pictures of the participant's faces in a 'happy smiling' and a 'sad frowning' conditions. Chimeric faces were constructed by mirroring right and left hemi-faces, as done in previous studies, resulting in a left mirrored and right mirrored chimeric face per picture. To gain measures of hemi-face dominance per participant, a jury of 20 additional participants rated which chimeric face shows higher intensity of emotional expressivity, by marking a 155mm line between the two versions. Measures of the asymmetry of the uncinate, the cingulum and the three branches of superior longitudinal fasciculi were derived from diffusion weighted imaging tractography dissections. Group effect analyses indicated that the degree of asymmetry in emotional expression was not as prominent as reported in the literature and showed a large inter-individual variability. The degree of asymmetry in emotional expression was, however, significantly associated with the asymmetries in connective properties of the frontotemporal and fronto-parietal tracts, specifically the uncinate fasciculus and the first branch of the

Domaines: Neurosciences; Psychologie; Neurosciences [q-bio.NC]; Psychologie et comportements

Stefano Ioannucci, Nathalie George, Patrick Friedrich, Leonardo Cerliani, Michel Thiebaut de Schotten. White matter correlates of hemi-face dominance in happy and sad expression. Brain Structure and Function, 2020, 225 (4), pp.1379-1388. ⟨10.1007/s00429-020-02040-7⟩. ⟨hal-03006212⟩