Inorganic ions in the skin: Allies or enemies?
Résumé
Skin constitutes a barrier protecting the organism against physical and chemical factors. Therefore, it is
constantly exposed to the xenobiotics, including inorganic ions that are ubiquitous in the environment. Some of
them play important roles in homeostasis and regulatory functions of the body, also in the skin, while others can
be considered dangerous. Many authors have shown that inorganic ions could penetrate inside the skin and
possibly induce local effects. In this review, we give an account of the current knowledge on the effects of skin
exposure to inorganic ions. Beneficial effects on skin conditions related to the use of thermal spring waters are
discussed together with the application of aluminium in underarm hygiene products and silver salts in treatment
of difficult wounds. Finally, the potential consequences of dermal exposure to topical sensitizers and harmful
heavy ions including radionuclides are discussed.
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