Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster

Kathryn Vaillancourt , Jennie Yang , Gary Chen , Volodymyr Yerko , Jean-François Théroux , Zahia Aouabed , Alberto Lopez , Kimberly Thibeault , Erin Calipari , Benoit Labonté , Naguib Mechawar , Carl Ernst , Corina Nagy , Thierry Forné (1) , Eric Nestler , Deborah Mash , Gustavo Turecki

1 IGMM - Institut de Génétique Moléculaire de Montpellier

Mots clés: cocaine; addiction; epigenetics; DNA methylation; 3C; 3D chromatin structure

Domaines: Génomique, Transcriptomique et Protéomique [q-bio.GN]

Kathryn Vaillancourt, Jennie Yang, Gary Chen, Volodymyr Yerko, Jean-François Théroux, et al.. Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster. Molecular Psychiatry, 2021, 26, pp.3134-3151. ⟨10.1038/s41380-020-00909-x⟩. ⟨hal-02989971⟩