Differential distribution of dystrophins in rat retina. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Investigative Ophthalmology & Visual Science Année : 1999

Differential distribution of dystrophins in rat retina.

Thomas Claudepierre
F Rodius
M Frasson
  • Fonction : Auteur
V Fontaine
  • Fonction : Auteur
S Picaud
  • Fonction : Auteur
H Dreyfus
  • Fonction : Auteur
D Mornet
  • Fonction : Auteur
A Rendon
  • Fonction : Auteur

Résumé

Duchenne muscular dystrophy is frequently associated with a reduced amplitude of b-wave under scotopic conditions in the electroretinogram. This suggests that the dystrophin gene-encoded proteins play a role in retinal neurotransmission. The abnormal neurotransmission has been attributed to altered expressions of C-terminal products of the dystrophin gene in the outer plexiform layer, where photoreceptor cells form synapses with secondary neurons. The present study was undertaken to determine the cellular distribution of each member of the dystrophin superfamily in rat retina.
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Dates et versions

hal-02986990 , version 1 (03-11-2020)

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  • HAL Id : hal-02986990 , version 1
  • PUBMED : 10359335

Citer

Thomas Claudepierre, F Rodius, M Frasson, V Fontaine, S Picaud, et al.. Differential distribution of dystrophins in rat retina.. Investigative Ophthalmology & Visual Science, 1999, 40 (7), pp.1520-9. ⟨hal-02986990⟩

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