Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus

Aurélie Perrin (1) , Anne-Sophie Gosselin-Grenet (2) , Marie Rossignol (3) , Carole Ginibre (3) , Bethsabée Scheid (1) , Christophe Lagneau (4) , Fabrice Chandre (3) , Thierry Baldet (5) , Mylène Ogliastro (2) , Jérémy Bouyer (5)

1 MIVEGEC - Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle
2 DGIMI - Diversité, Génomes & Interactions Microorganismes - Insectes [Montpellier]
3 MIVEGEC-VCG - Vector Control Group
4 EID - Entente Interdépartementale pour la démoustication du littoral méditerranéen
5 UMR ASTRE - Animal, Santé, Territoires, Risques et Ecosystèmes

Urban Aedes mosquitoes are vectors of many viruses affecting human health such as dengue, chikungunya and Zika viruses. Insecticide resistance and environmental toxicity risks hamper the effectiveness of chemical control against these mosquito vectors. Alternative control methods, such as the use of mosquito-specific entomopathogenic viruses should be explored. Numerous studies have focused on evaluating the potential of different densoviruses species as biological control agents. However, knowledge on the extent of inter-and intra-specific variations in the susceptibility of Aedes mosquitoes to infection by different densoviruses remains insufficient. In this study, we compared infection and mortality rates induced by the Aedes albopictus densovirus 2 in different strains of Aedes albopictus and Aedes aegypti mosquitoes. The two Aedes species were different in terms of susceptibility to viral infection. Under laboratory conditions, Aedes albopictus densovirus 2 appeared more virulent for the different strains of Aedes aegypti tested than for those of Aedes albopictus. In addition, we also found significant intra-specific variation in infection and mortality rates. Thus, although even if Aedes albopictus densoviruses could be powerful biocontrol agents used in the management of urban Aedes populations, our results also call into question the use of single viral isolate as biocontrol agents.

Domaines: Zoologie des invertébrés

Aurélie Perrin, Anne-Sophie Gosselin-Grenet, Marie Rossignol, Carole Ginibre, Bethsabée Scheid, et al.. Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus. Scientific Reports, 2020, 10, ⟨10.1038/s41598-020-75765-4⟩. ⟨hal-02985676⟩