18FDG PET/CT in the early assessment of non-small cell lung cancer response to immunotherapy: frequency and clinical significance of atypical evolutive patterns

Olivier Humbert (1, 2) , Nour Cadour (1, 3) , R. Schiappa (1) , M. Poudenx (1) , D. Chardin (1, 2) , D. Borchiellini (1) , D. Benisvy (1) , M. Ouvrier (1) , C. Zwarthoed (1) , A. Schiazza (1) , M. Ilie (4) , H. Ghalloussi (1) , P. Koulibaly (1) , J. Darcourt (1) , J. Otto (1)

1 UNICANCER/CAL - Centre de Lutte contre le Cancer Antoine Lacassagne [Nice]
2 TIRO-MATOs UMR E4320 - Transporteurs et Imagerie, Radiothérapie en Oncologie et Mécanismes biologiques des Altérations du Tissu Osseux
3 CHU Nîmes - Centre Hospitalier Universitaire de Nîmes
4 OncoAge - FHU OncoAge - Pathologies liées à l’âge [CHU Nice]

This prospective study aimed (1) to assess the non-small cell lung cancer (NSCLC) evolutive patterns to immunotherapy using FDG-PET and (2) to describe their association with clinical outcome.

Mots clés: FDG PET; Immunotherapy; Lung cancer; Monitoring; Response

Domaines: Imagerie; Médecine nucléaire; Médecine humaine et pathologie

Olivier Humbert, Nour Cadour, R. Schiappa, M. Poudenx, D. Chardin, et al.. 18FDG PET/CT in the early assessment of non-small cell lung cancer response to immunotherapy: frequency and clinical significance of atypical evolutive patterns. European Journal of Nuclear Medicine and Molecular Imaging, 2020, 47 (5), pp.1158-1167. ⟨10.1007/s00259-019-04573-4⟩. ⟨hal-02563277⟩