Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies, Lancet, vol.390, pp.2769-2778, 2018. ,
Regional ileitis: a pathologic and clinical entity, Mt. Sinai J. Med, vol.67, pp.263-268, 2000. ,
Crohn's disease, The Lancet, vol.389, pp.1741-1755, 2017. ,
Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway, Inflamm. Bowel Dis, vol.18, pp.889-899, 2012. ,
Identification of disease-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease, Clin. Genet, vol.80, pp.59-67, 2011. ,
Identification of disease-associated DNA methylation in B cells from Crohn's disease and ulcerative colitis patients, Dig. Dis. Sci, vol.57, pp.3145-3153, 2012. ,
Genome-wide analysis of DNA methylation and gene expression defines molecular characteristics of Crohn's disease-associated fibrosis, Clin. Epigenetics, vol.8, p.30, 2016. ,
DNA methylation profiling in inflammatory bowel disease provides new insights into disease pathogenesis, J. Crohns Colitis, vol.10, pp.77-86, 2016. ,
Peripheral blood methylation profiling of female Crohn's disease patients, Clin. Epigenetics, vol.8, p.65, 2016. ,
A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn's disease patients, PLoS ONE, vol.13, p.209656, 2018. ,
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease, Nat. Commun, vol.7, p.13507, 2016. ,
Blood-derived DNA methylation signatures of Crohn's disease and severity of intestinal inflammation, Gastroenterology, vol.156, pp.2254-2265, 2019. ,
Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics, Gastroenterology, vol.145, pp.293-308, 2013. ,
Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation, J. Nutr. Biochem, vol.23, pp.853-859, 2012. ,
Associations between folate and vitamin B12 levels and inflammatory bowel disease: a meta-analysis, Nutrients, vol.9, p.382, 2017. ,
The relevance of vitamin and iron deficiency in patients with inflammatory bowel diseases in patients of the swiss IBD cohort, Inflamm. Bowel Dis, vol.24, pp.1768-1779, 2018. ,
Status of serum vitamin B12 and folate in patients with inflammatory bowel disease in China, Intest. Res, vol.15, pp.103-108, 2017. ,
Frequency, types, and treatment of anemia in Turkish patients with inflammatory bowel disease, World J. Gastroenterol, vol.24, pp.4186-4196, 2018. ,
Should we monitor vitamin B12 and folate levels in Crohn's disease patients?, Scand. J. Gastroenterol, vol.48, pp.1272-1277, 2013. ,
Serum vitamin B12 and folate status in patients with inflammatory bowel diseases, Eur. J. Intern. Med, vol.21, pp.320-323, 2010. ,
Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease, Gastroenterology, vol.115, pp.1405-1413, 1998. ,
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease, Gastroenterology, vol.127, pp.412-421, 2004. ,
Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells, Int. J. Med. Microbiol, vol.298, pp.397-409, 2008. ,
Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer, Gastroenterology, vol.127, pp.80-93, 2004. ,
Molecular diversity of Escherichia coli in the human gut: new ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease, Inflamm. Bowel Dis, vol.15, pp.872-882, 2009. ,
Adherent-invasive Escherichia coli in inflammatory bowel disease, Gut, vol.67, pp.574-587, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01681169
Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM, J. Exp. Med, vol.206, pp.2179-2189, 2009. ,
CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease, J. Clin. Investig, vol.117, pp.1566-1574, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-02666899
Adherent-invasive E. coli: update on the lifestyle of a troublemaker in Crohn's disease, Int. J. Mol. Sci, vol.21, p.3734, 2020. ,
URL : https://hal.archives-ouvertes.fr/hal-02917127
Novel mouse model for carcinoembryonic antigen-based therapy, Mol. Ther, vol.9, pp.775-785, 2004. ,
Diet-induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia coli colonisation, Gut, vol.64, pp.428-437, 2015. ,
Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring, J. Nutr, vol.132, pp.2393-2400, 2002. ,
Dietary and supplemental maternal methyl-group donor intake and cord blood DNA methylation, Epigenetics, vol.12, pp.1-10, 2017. ,
Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology, Genes Nutr, vol.12, p.22, 2017. ,
Prenatal methyl-donor supplementation augments colitis in young adult mice, PLoS ONE, vol.8, p.73162, 2013. ,
Methyl deficient diet aggravates experimental colitis in rats, J. Cell. Mol. Med, vol.15, pp.2486-2497, 2011. ,
Methyl donor deficiency affects small-intestinal differentiation and barrier function in rats, Br. J. Nutr, vol.109, pp.667-677, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-01704507
Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat, Am. J. Pathol, vol.176, pp.270-277, 2010. ,
Faecal chitinase 3-like 1 is a reliable marker as accurate as faecal calprotectin in detecting endoscopic activity in adult patients with inflammatory bowel diseases, Aliment. Pharmacol. Ther, vol.43, pp.1069-1079, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-02639968
Environmental risk factors for inflammatory bowel diseases: an umbrella review of meta-analyses, Gastroenterology, vol.157, pp.647-659, 2019. ,
Faecal and serum metabolomics in paediatric inflammatory bowel disease, J. Crohns Colitis, vol.11, pp.321-334, 2017. ,
DNA methylation and transcription patterns in intestinal epithelial cells from pediatric patients with inflammatory bowel diseases differentiate disease subtypes and associate with outcome, Gastroenterology, vol.154, pp.585-598, 2018. ,
, Scientific RepoRtS |, vol.10, p.12922, 2020.
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci, Nat. Genet, vol.42, pp.1118-1125, 2010. ,
Maternal micronutrients can modify colonic mucosal microbiota maturation in murine offspring, Gut Microbes, vol.3, pp.426-433, 2012. ,
Excess of methyl donor in the perinatal period reduces postnatal leptin secretion in rat and interacts with the effect of protein content in diet, PLoS ONE, vol.8, p.68268, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02647689
Point mutations in FimH adhesin of Crohn's disease-associated adherent-invasive Escherichia coli enhance intestinal inflammatory response, PLoS Pathog, vol.9, p.1003141, 2013. ,
Chitin-binding domains of Escherichia Coli ChiA mediate interactions with intestinal epithelial cells in mice with colitis, Gastroenterology, vol.145, p.9, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02651692
From bacterial killing to immune modulation: recent insights into the functions of lysozyme, PLoS Pathog, vol.13, p.1006512, 2017. ,
The functions and therapeutic potential of heat shock proteins in inflammatory bowel disease-an update, IJMS, vol.20, p.5331, 2019. ,
Resistance to experimental colitis depends on cytoprotective heat shock proteins in macrophage migration inhibitory factor null mice, Immunol. Lett, vol.107, pp.148-154, 2006. ,
IgA responses to microbiota, Immunity, vol.49, pp.211-224, 2018. ,
High-avidity IgA protects the intestine by enchaining growing bacteria, Nature, vol.544, pp.498-502, 2017. ,
Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease, Cell, vol.158, pp.1000-1010, 2014. ,
IgA-coated E. coli enriched in Crohn's disease spondyloarthritis promote TH17-dependent inflammation, Sci. Transl. Med, vol.9, p.9655, 2017. ,
Clinical significance of soluble immunoglobulins A and G and their coated bacteria in feces of patients with inflammatory bowel disease, J. Transl. Med, vol.16, p.359, 2018. ,
Immunoglobulin coating of faecal bacteria in inflammatory bowel disease, Eur. J. Gastroenterol. Hepatol, vol.16, pp.669-674, 2004. ,
Crohn's disease patients have more IgG-binding fecal bacteria than controls, Clin. Vaccine Immunol, vol.19, pp.515-521, 2012. ,
Nutrition assessment of patients with inflammatory bowel disease, JPEN J. Parenter. Enter. Nutr, vol.31, pp.311-319, 2007. ,
Vitamin and mineral status in patients with inflammatory bowel disease, J. Pediatr. Gastroenterol. Nutr, vol.56, pp.89-92, 2013. ,
New insights into the role of trace elements in IBD, Biomed. Res. Int, pp.1-9, 2018. ,
Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation, Mol. Nutr. Food Res, vol.59, pp.991-999, 2015. ,
Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohn's disease patients, Inflamm. Bowel Dis, vol.18, pp.294-304, 2012. ,
Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation, PLoS ONE, vol.7, p.44328, 2012. ,