NAA50 is an enzymatically active Nα-acetyltransferase that is crucial for development and regulation of stress responses

Laura Armbruster (1) , Eric Linster (2) , Jean-Baptiste Boyer (3) , Annika Brünje (4) , Jürgen Eirich (4) , Iwona Stephan (1) , Willy V. Bienvenut (5, 6) , Jonas Weidenhausen (7) , Thierry Meinnel (5, 6) , Ruediger Hell (8) , Irmgard Sinning (7) , Iris Finkemeier (4) , Carmela Giglione (5, 6) , Markus Wirtz (1)

1 Universität Heidelberg [Heidelberg] = Heidelberg University
2 Hartmut Hoffmann-Berling International Graduate School
3 IMB - Institut de Mathématiques de Bordeaux
4 WWU - Westfälische Wilhelms-Universität Münster = University of Münster
5 PROMTI - Maturation des proteines, destinée cellulaire et thérapeutique
6 I2BC - Institut de Biologie Intégrative de la Cellule
7 Heidelberg University Biochemistry Center
8 HIP - Heidelberger Institut für Pflanzenwissenschaften

Arabidopsis 3 Short title: NatB acetylates 20% of the proteome in Arabidopsis 4 One Sentence Summary: Functional characterization of the plant NatB complex 5 reveals the evolutionary conservation of initiator methionine acetylation and its 6 consequences for adaptation of Arabidopsis to abiotic stresses. 7 8 28 29 Author contributions: MH, EL and ISt identified and characterized the NatB depleted 30 mutants under non-stressed and osmotic stress conditions. CG and TM supervised the N-31 terminal acetylome profiling. WVB profiled N-termini of the NatB depleted mutants and wild-32 type. CG, TM and WVB analyzed the N-termini data. CS performed the global transcriptome 33

Domaines: Sciences du Vivant [q-bio]; Biochimie, Biologie Moléculaire; Biologie structurale [q-bio.BM]; Génomique, Transcriptomique et Protéomique [q-bio.GN]; Organisation et fonctions cellulaires [q-bio.SC]; Biologie du développement

Laura Armbruster, Eric Linster, Jean-Baptiste Boyer, Annika Brünje, Jürgen Eirich, et al.. NAA50 is an enzymatically active Nα-acetyltransferase that is crucial for development and regulation of stress responses. Plant Physiology, 2020, 182 (2), pp.792-806. ⟨10.1104/pp.20.00222⟩. ⟨hal-02900665⟩