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Reasons for the Failure of Platelet Function Testing to Adjust Antiplatelet Therapy

Abstract : In the ARCTIC trial (Assessment by a Double Randomization of a Conventional Antiplatelet Strategy Versus a Monitoring-Guided Strategy for Drug-Eluting Stent Implantation and of Treatment Interruption Versus Continuation One Year After Stenting), treatment adjustment following platelet function testing failed to improve clinical outcomes. However, high-on-treatment platelet reactivity (HPR) is considered as a predictor of poor ischemic outcome. This prespecified substudy evaluated clinical outcomes according to the residual platelet reactivity status after antiplatelet therapy adjustment.
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https://hal.archives-ouvertes.fr/hal-02869075
Contributor : Mélanie Karli <>
Submitted on : Monday, June 15, 2020 - 6:00:34 PM
Last modification on : Wednesday, July 8, 2020 - 3:01:30 AM

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Benoit Lattuca, Johanne Silvain, Yan Yan, Christophe Pouillot, Thomas Cuisset, et al.. Reasons for the Failure of Platelet Function Testing to Adjust Antiplatelet Therapy. Circulation: Cardiovascular Interventions, American Heart Association, 2019, 12 (11), pp.e007749. ⟨10.1161/CIRCINTERVENTIONS.118.007749⟩. ⟨hal-02869075⟩

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