Carbapenemase-producing Enterobacteriaceae among pregnant women and newborns in Algeria: Prevalence, molecular characterization, maternal-neonatal transmission, and risk factors for carriage

Assia Mairi (1, 2) , Abdelaziz Touati (2) , Sylia Ait Bessai (2) , Yasmina Boutabtoub (2) , Fazia Khelifi (2) , Albert Sotto (1, 3) , Jean-Philippe Lavigne (1, 3) , Alix Pantel (1, 3)

1 VBMI - Virulence bactérienne et maladies infectieuses
2 UB - Université Abderrahmane Mira [Université de Béjaïa] = University Abderrahmane Mira [University of Béjaïa]
3 CHU Nîmes - Centre Hospitalier Universitaire de Nîmes

The diffusion of carbapenemase-producing Enterobacteriaceae (CPE) represents a worldwide public health problem. This study revealed that the prevalence of OXA-48-producing enterobacteria was 4.6% (19/414) and 1.6% (7/422) in mothers and newborns, respectively, from 2 maternity units in Algeria. Previous hospital admission was an independent factor associated with an increased risk of CPE carriage in the mothers (P = .021). The low birth weight was significantly associated with this carriage in the newborns (P = .008). The screening of these bacteria is essential to prevent the dissemination of CPE.

Mots clés: Algeria; Enterobacteriaceae; Mother-newborn pairs; OXA-48; Outbreak; Transmission

Domaines: Santé publique et épidémiologie; Maladies infectieuses

Assia Mairi, Abdelaziz Touati, Sylia Ait Bessai, Yasmina Boutabtoub, Fazia Khelifi, et al.. Carbapenemase-producing Enterobacteriaceae among pregnant women and newborns in Algeria: Prevalence, molecular characterization, maternal-neonatal transmission, and risk factors for carriage. American Journal of Infection Control, 2019, 47 (1), pp.105-108. ⟨10.1016/j.ajic.2018.07.009⟩. ⟨hal-02866557⟩