The pig: a model for human infectious diseases - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Trends in Microbiology Année : 2012

The pig: a model for human infectious diseases

Résumé

An animal model to study human infectious diseases should accurately reproduce the various aspects of disease. Domestic pigs (Sus scrofa domesticus) are closely related to humans in terms of anatomy, genetics and physiology, and represent an excellent animal model to study various microbial infectious diseases. Indeed, experiments in pigs are much more likely to be predictive of therapeutic treatments in humans than experiments in rodents. In this review, we highlight the numerous advantages of the pig model for infectious disease research and vaccine development and document a few examples of human microbial infectious diseases for which the use of pigs as animal models has contributed to the acquisition of new knowledge to improve both animal and human health.

Mots clés

Dates et versions

hal-02652897 , version 1 (29-05-2020)

Identifiants

Citer

Francois Meurens, Artur Summerfield, Hans Nauwynck, Linda Saif, Volker Gerdts. The pig: a model for human infectious diseases. Trends in Microbiology, 2012, 20 (1), pp.50-57. ⟨10.1016/j.tim.2011.11.002⟩. ⟨hal-02652897⟩
5 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More