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, Abbreviations used in this paper: ANOVA: analysis of variance; BM: Bone Metastases

B. Bv/, TV: Bone Volume/Tissues Volume; CCL17-CCL20: Chemokine (C-C motif) ligand 17

, CCR4 and CCR6: C-C chemokine receptor type 4 and 6; ERR: estrogen receptor-related receptor

, LAMP-1: Lysosome-associated membrane glycoprotein-1; LM: Lung Metastases; OCs: osteoclasts; RANKL: receptor activator of nuclear factor kB ligand

, PCR: polymerase chain reaction; PMN-MDSC: Poly-MorphoNuclear Myeloid Derived Suppressor cells; TNBC: Triple-negative breast cancer; TGF-?: Transforming Growth Factor Beta

. Tb/stv,