Skip to Main content Skip to Navigation
Poster communications

Ferritin iron core, Actinide uptake by transferrin and ferritin metalloproteins: two EXAFS studies

Abstract : In order to better understand the mechanisms of actinide uptakeby specific biomolecules, it is essential to explore the intramolecular interactions between the cation and the protein binding site. Although this has long been done for widely investigated transition metals, very few studies have been devoted to complexation mechanisms of actinides by active chelation sitesof metalloproteins. In this field, X-ray absorption spectroscopy has been extensively used as a structural and electronic metal cation probe. The two examples that are presented here are related totwo metalloproteins in charge of iron transport and storage in eukaryote cells: transferrin and ferritin. U(VI)O22+, Np(IV) and Pu(IV) have been selected because of their possible role as contaminant from the geosphere.
Document type :
Poster communications
Complete list of metadata

https://hal.archives-ouvertes.fr/hal-02535591
Contributor : Cécile Barbot <>
Submitted on : Friday, April 10, 2020 - 5:00:10 PM
Last modification on : Sunday, April 26, 2020 - 12:10:03 PM

File

Poster AECCPCM A4 2008.pdf
Files produced by the author(s)

Identifiers

  • HAL Id : hal-02535591, version 1

Collections

Citation

C. Barbot, Christophe den Auwer, Guy Ouvrard, Isabelle Llorens, Philippe Moisy, et al.. Ferritin iron core, Actinide uptake by transferrin and ferritin metalloproteins: two EXAFS studies. AECCPCM, Apr 2008, Marseille, France. ⟨hal-02535591⟩

Share

Metrics

Record views

35

Files downloads

22