Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site

Willy Bogers , Susan W Barnett (1) , Herman Oostermeijer , Ivonne Nieuwenhuis , Niels Beenhakker , Daniella Mortier , Petra Mooij , Gerrit Koopman , Edmund Remarque , Grégoire Martin (2, 3) , Rachel Pei-Jen Lai , Antu Dey (4) , Yide Sun (4) , Brian Burke (5) , Guido Ferrari , David C. Montefiori (6) , Loïc M Martin (2, 3) , David Davis , Indresh Srivastava (4) , Jonathan Heeney

1 Novartis Vaccines
2 MTS - Médicaments et Technologies pour la Santé
3 SIMoS - Service d'Ingénierie Moléculaire pour la Santé (ex SIMOPRO)
4 Novartis Vaccines and Diagnostics [Siena]
5 Department of Anatomy and Cell Biology
6 Duke Human Vaccine Institute [Durham, North Carolina, USA]

Domaines: Chimie thérapeutique; Médecine vétérinaire et santé animale; Biochimie [q-bio.BM]; Immunothérapie; Vaccinologie; Virologie

Willy Bogers, Susan W Barnett, Herman Oostermeijer, Ivonne Nieuwenhuis, Niels Beenhakker, et al.. Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site. Journal of Virology, 2017, 91 (19), ⟨10.1128/JVI.00811-17⟩. ⟨hal-02530939⟩