Interfacial Cavity Filling To Optimize CD4–Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein

Laurence Morellato-Castillo (1) , Priyamvada Acharya (2) , Olivier Combes , Johan Michiels (3) , Anne Descours , Oscar Ramos , Yongping Yang (2) , Guido Vanham (4) , Kevin Ariën , Peter D. Kwong (2) , Loïc M Martin (1) , Pascal Kessler (1)

1 DRF (CEA) - Direction de Recherche Fondamentale (CEA)
2 Vaccine Research Center
3 ITM - Institute of Tropical Medicine [Antwerp]
4 Department of Microbiology

Domaines: Cristallographie; Chimie thérapeutique; Biochimie [q-bio.BM]; Biologie structurale [q-bio.BM]; Immunothérapie; Médicaments

Laurence Morellato-Castillo, Priyamvada Acharya, Olivier Combes, Johan Michiels, Anne Descours, et al.. Interfacial Cavity Filling To Optimize CD4–Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein. Journal of Medicinal Chemistry, 2013, 56 (12), pp.5033-5047. ⟨10.1021/jm4002988⟩. ⟨hal-02530667⟩