Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1

Priyamvada Acharya (1) , Timothy S. Luongo (1) , Mark k. Louder , Krisha Mckee , Yongping Yang (1) , Young Do kwon , John r. Mascola , Pascal Kessler (2) , Loïc M Martin (2) , Peter d. Kwong (3)

1 Vaccine Research Center
2 DRF (CEA) - Direction de Recherche Fondamentale (CEA)
3 VRC - Vaccine Research Center

Domaines: Chimie thérapeutique; Cristallographie; Biochimie [q-bio.BM]; Biologie structurale [q-bio.BM]; Médicaments

Priyamvada Acharya, Timothy S. Luongo, Mark k. Louder, Krisha Mckee, Yongping Yang, et al.. Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1. Structure, 2013, 21 (6), pp.1018-1029. ⟨10.1016/j.str.2013.04.015⟩. ⟨hal-02530653⟩