BIOMIMETIC IONIC MICROSTIMULATION FOR NEURON CULTURE - Archive ouverte HAL Accéder directement au contenu
Communication Dans Un Congrès Année : 2018

BIOMIMETIC IONIC MICROSTIMULATION FOR NEURON CULTURE

Résumé

Here, we propose a novel microfluidic system to investigate the response of the neurons directly stimulated by the potassium ions in vitro. Unlike the conventional way of stimulating neurons by pipetting or sending electrical stimulus, this biomimetic stimulation system enables precise and rapid control of ion concentration by utilizing microfluidic pneumatic valves, which mimics physiological stimulation in a body. By using the system, we demonstrated stimulations of the neuron cells with potassium ions and monitored neural activities with a calcium-specific fluorescence indicator.
Fichier principal
Vignette du fichier
Abstract_ISMM_v8.pdf (127.11 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-02484018 , version 1 (19-02-2020)

Identifiants

  • HAL Id : hal-02484018 , version 1

Citer

Stephany Mai Nishikawa, Soo Hyeon Kim, Yoshiho Ikeuchi, Teruo Fujii, Timothée Levi. BIOMIMETIC IONIC MICROSTIMULATION FOR NEURON CULTURE. 10th International Symposium on Microchemistry and Microsystems (ISMM2018), Jun 2018, Busan, South Korea. ⟨hal-02484018⟩
25 Consultations
12 Téléchargements

Partager

Gmail Facebook X LinkedIn More