Tracking the acquisition of anticipatory postural adjustments during a bimanual load-lifting task: A MEG study

Franck Di Rienzo (1, 2) , Fanny Barlaam (2) , Sébastien Daligault (3) , Claude Delpuech (2, 3) , Alice C Roy (4) , Olivier Bertrand (2) , Karim Jerbi (5) , Christina Schmitz (2)

1 LIBM - Laboratoire Interuniversitaire de Biologie de la Motricité
2 CRNL - Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center
3 CERMEP - Imagerie du vivant
4 DDL - Dynamique Du Langage
5 UdeM - Université de Montréal

During bimanual coordination, that is, manipulating with the dominant hand an object held by the postural hand, anticipatory postural adjustments are required to cancel the perturbations and ensure postural stabilization. Using magnetoencephalography (MEG), we investigated changes mediating the acquisition of anticipatory postural adjustments during a bimanual load-lifting task. Participants lifted a load with their right hand, hence triggering the fall of a second load fixed to their left (postural) forearm. During ACQUISITION, the onset of load-lifting and the fall of the second load were experimentally delayed after few trials. During CONTROL, load-lifting triggered the fall of the second load without delay. Upward elbow rotation decreased with trial repetition during ACQUISITION, hence attesting the ongoing acquisition of anticipatory postural adjustments. Bilateral event-related desynchronisation (ERD) of the alpha rhythm (8-12 Hz) was recorded. Generators of the mu rhythm were found within central and associative motor regions. Their spatial distribution within the hemisphere contralateral to the load-lifting arm was less refined and circumscribed during ACQUISITION compared to CONTROL. Regression analyses emphasized the specific involvement of the precuneus in the right hemisphere contralateral to the postural forearm, and a medial prefrontal region in the left hemisphere. Analyses of the time course power showed that an increase in preunloading activation within the precuneus and a decrease in postunloading inhibition within the medial prefrontal region were associated with the acquisition of anticipatory postural adjustments. The study provides original insights into cortical activations mediating the progressive tuning of anticipatory postural adjustments during the acquisition stage of motor learning.

Mots clés: motor control; bimanual coordination; mu sensorimotor rhythm; neural plasticity

Domaines: Neurosciences

Franck Di Rienzo, Fanny Barlaam, Sébastien Daligault, Claude Delpuech, Alice C Roy, et al.. Tracking the acquisition of anticipatory postural adjustments during a bimanual load-lifting task: A MEG study. Human Brain Mapping, 2019, 40 (10), pp.2955-2966. ⟨10.1002/hbm.24571⟩. ⟨hal-02379153⟩