A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase

Jan Paeshuyse (1) , Carine Letellier (2) , Matheus Froeyen (3) , Hélène Dutartre (4) , Robert Vrancken , Bruno Canard (5) , Erik de Clercq , Alain Gueiffier (6) , Jean-Claude Teulade (7) , Piet Herdewijn (8) , Gerhard Puerstinger , Frank Koenen , Pierre Kerkhofs , Pier Giovanni Baraldi , Johan Neyts (1)

1 Department of Microbiology and Immunology, Rega Institute for Medical Research
2 Department of Virology
3 Laboratory of Medicinal Chemistry
4 OR - Oncogenèse rétrovirale – Retroviral Oncogenesis
5 AFMB - Architecture et fonction des macromolécules biologiques
6 UT - Université de Tours
7 IMTV - Imagerie Moléculaire et Thérapie Vectorisée
8 Laboratory for Medicinal Chemistry

Domaines: Virologie

Jan Paeshuyse, Carine Letellier, Matheus Froeyen, Hélène Dutartre, Robert Vrancken, et al.. A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase. Antiviral Research, 2009, 82 (3), pp.141-147. ⟨10.1016/j.antiviral.2009.02.192⟩. ⟨hal-02459207⟩