Isolation of Nontuberculous Mycobacteria in Southeast Asian and African Human Immunodeficiency Virus-infected Children With Suspected Tuberculosis

Laurence Borand , Agathe de Lauzanne , N.L. Nguyen , Sokleaph Cheng , Thu Hang Pham , Sara C Eyangoh , Abdoul Salam Ouedraogo , Vibol Ung , Philippe Msellati (1) , Mathurin Tejiokem , Boubacar Nacro , Malin Inghammar , Dim Bunnet , Christophe Delacourt , Sylvain Godreuil (2) , Stephane Blanche , Olivier Marcy (3)

1 TransVIHMI - Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques et émergentes
2 CHU Montpellier
3 BPH - Bordeaux population health

We enrolled 427 human immunodeficiency virus-infected children (median age, 7.3 years), 59.2% severely immunodeficient, with suspected tuberculosis in Southeast Asian and African settings. Nontuberculous mycobacteria were isolated in 46 children (10.8%); 45.7% of isolates were Mycobacterium avium complex. Southeast Asian origin, age 5-9 years, and severe immunodeficiency were independently associated with nontuberculous mycobacteria isolation.

Mots clés: HIV; children; nontuberculous mycobacteria; tuberculosis

Domaines: Sciences du Vivant [q-bio]; Médecine humaine et pathologie

Laurence Borand, Agathe de Lauzanne, N.L. Nguyen, Sokleaph Cheng, Thu Hang Pham, et al.. Isolation of Nontuberculous Mycobacteria in Southeast Asian and African Human Immunodeficiency Virus-infected Children With Suspected Tuberculosis. Clinical Infectious Diseases, 2019, 68 (10), pp.1750-1753. ⟨10.1093/cid/ciy897⟩. ⟨hal-02440946⟩