Evolution and Function of Thioester-Containing Proteins and the Complement System in the Innate Immune Response, Front. Immunol, vol.8, p.759, 2017. ,
Thioester-containing proteins: At the crossroads of immune effector mechanisms, vol.8, pp.1468-1470, 2017. ,
The phylogeny and evolution of the thioester bond-containing proteins C3, C4 and ?2-macroglobulin, Immunol. Rev, vol.166, pp.15-26, 1998. ,
The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism, Biochem. J, vol.133, pp.709-724, 1973. ,
Proteases and protease inhibitors: A balance of activities in host-pathogen interaction, Immunobiology, vol.211, pp.263-281, 2006. ,
Alpha2-macroglobulin: An evolutionarily conserved arm of the innate immune system, Dev. Comp. Immunol, vol.23, pp.375-390, 1999. ,
, Structure and Function. Sub-Cell. Biochem, vol.83, pp.149-183, 2017.
alpha-2-Macroglobulin: A physiological guardian, J. Cell. Physiol, vol.228, pp.1665-1675, 2013. ,
, Annu. Rev. Biochem, vol.44, pp.697-724, 1975.
Complement component C3-The "Swiss Army Knife" of innate immunity and host defense, Immunol. Rev, vol.274, pp.33-58, 2016. ,
Complement: A key system for immune surveillance and homeostasis, Nat. Immunol, vol.11, pp.785-797, 2010. ,
The complement C3 protein family in invertebrates, Invertebr. Surviv. J, vol.8, pp.21-32, 2011. ,
Analysis of Thioester-Containing Proteins during the Innate Immune Response of Drosophila melanogaster, J. Innate Immun, vol.3, pp.52-64, 2010. ,
Constitutive expression of a complement-like protein in toll and JAK gain-of-function mutants of Drosophila, Proc. Natl. Acad. Sci, vol.97, pp.11427-11432, 2000. ,
URL : https://hal.archives-ouvertes.fr/hal-02333168
Identification of Drosophila Gene Products Required for Phagocytosis of Candida albicans, PLoS Biol, 2006. ,
Structural basis for conserved complement factor-like function in the antimalarial protein TEP1, Proc. Natl. Acad. Sci, vol.104, pp.11615-11620, 2007. ,
Functional Genomics of Tick Thioester-Containing Proteins Reveal the Ancient Origin of the Complement System, J. Innate Immun, vol.3, pp.623-630, 2011. ,
Eleftherianos, I. Drosophila anti-nematode and antibacterial immune regulators revealed by RNA-Seq, BMC Genom, p.519, 2015. ,
Eleftherianos, I. The distinct function of Tep2 and Tep6 in the immune defense of Drosophila melanogaster against the pathogen Photorhabdus, vol.8, pp.1668-1682, 2017. ,
Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps, BMC Biol, vol.15, p.79, 2017. ,
Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae, Cell, vol.116, pp.661-670, 2004. ,
Antimalarial Responses in Anopheles gambiae: From a Complement-like Protein to a Complement-like Pathway, Cell Host Microbe, vol.3, pp.364-374, 2008. ,
An in vivo transfection approach elucidates a role for Aedes aegypti thioester-containing proteins in flaviviral infection, PLoS ONE, vol.6, 2011. ,
Complement-related proteins control the flavivirus infection of Aedes aegypti by inducing antimicrobial peptides, PLoS Pathog, vol.10, p.1004027, 2014. ,
Identification, molecular characterization, and gene expression analysis of a CD109 molecule in the Hawaiian bobtail squid Euprymna scolopes, Fish Shellfish Immunol, vol.44, pp.342-355, 2015. ,
Molecular cloning of alpha2-macroglobulin in sea scallop Chlamys farreri (Bivalvia, Mollusca), Fish Shellfish Immunol, vol.18, pp.345-349, 2005. ,
The fragmentation mechanism and immune-protective effect of CfTEP in the scallop Chlamys farreri, Dev. Comp. Immunol, vol.76, pp.220-228, 2017. ,
Molecular cloning and characterization of a thioester-containing protein from Zhikong scallop Chlamys farreri, Mol. Immunol, vol.44, pp.3492-3500, 2007. ,
Immune repertoire in the transcriptome of Littorina littorea reveals new trends in lophotrochozoan proto-complement evolution, Dev. Comp. Immunol, vol.84, pp.250-263, 2018. ,
The Compatibility Between Biomphalaria glabrata Snails and Schistosoma mansoni: An Increasingly Complex Puzzle, Adv. Parasitol, vol.97, pp.111-145, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01511043
Schistosomiasis from a Snail's Perspective: Advances in Snail Immunity, Trends Parasitol, vol.33, pp.845-857, 2017. ,
Integrated multi-omic analyses in Biomphalaria-Schistosoma dialogue reveal the immunobiological significance of FREP-SmPoMuc interaction, Dev. Comp. Immunol, vol.75, pp.16-27, 2017. ,
The compatibiuty polymorphism in invertebrate host/trematodes interactions: Research of molecular determinants, Parasite, vol.15, pp.304-309, 2008. ,
Compatibility polymorphism in snail/schistosome interactions: From field to theory to molecular mechanisms, Dev. Comp. Immunol, vol.37, pp.1-8, 2012. ,
URL : https://hal.archives-ouvertes.fr/halsde-00631055
Are Biomphalaria snails resistant to Schistosoma mansoni?, J. Helminthol, vol.79, pp.187-191, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00104688
Parasite-host coevolution and geographic patterns of parasite infectivity and host susceptibility, Proceedings, vol.263, pp.119-128, 1996. ,
Selective pressure in host-parasite systems, J. Soc. Biol, vol.194, pp.19-23, 2000. ,
Biomphalysin, a New ? Pore-forming Toxin Involved in Biomphalaria glabrata Immune Defense against Schistosoma mansoni, PLoS Pathog, issue.9, 2013. ,
URL : https://hal.archives-ouvertes.fr/halsde-00823685
A large repertoire of parasite epitopes matched by a large repertoire of host immune receptors in an invertebrate host/parasite model, PLoS Negl. Trop. Dis, p.813, 2010. ,
A family of fibrinogen-related proteins that precipitates parasite-derived molecules is produced by an invertebrate after infection, Proc. Natl. Acad. Sci, vol.94, pp.8691-8696, 1997. ,
Controlled Chaos of Polymorphic Mucins in a Metazoan Parasite (Schistosoma mansoni) Interacting with Its Invertebrate Host (Biomphalaria glabrata), PLoS Negl. Trop. Dis, vol.2, p.330, 2008. ,
URL : https://hal.archives-ouvertes.fr/halsde-00344615
A multistrain approach to studying the mechanisms underlying compatibility in the interaction between Biomphalaria glabrata and Schistosoma mansoni, PLoS Negl. Trop. Dis, p.5398, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01511153
An example of molecular co-evolution: Reactive oxygen species (ROS) and ROS scavenger levels in Schistosoma mansoni/Biomphalaria glabrata interactions, Int. J. Parasitol, vol.41, pp.721-730, 2011. ,
URL : https://hal.archives-ouvertes.fr/halsde-00580768
Proteomic analysis of Biomphalaria glabrata plasma proteins with binding affinity to those expressed by early developing larval Schistosoma mansoni, PLoS Pathog, p.1006081, 2017. ,
BgTEP: An Antiprotease Involved in Innate Immune Sensing in Biomphalaria glabrata, Front. Immunol, vol.9, p.1206, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01838951
Purification and characterization of a tetrameric alpha-macroglobulin proteinase inhibitor from the gastropod mollusc Biomphalaria glabrata, Biochem. J, vol.316, pp.893-900, 1996. ,
Proteinase inhibitory activity in the plasma of a mollusc: Evidence for the presence of alpha-macroglobulin in Biomphalaria glabrata, Comp. Biochem. Physiol. B Comp. Biochem, vol.102, pp.821-824, 1992. ,
Inhibition of cysteine proteinase from Schistosoma mansoni larvae by alpha-macroglobulin from the plasma of Biomphalaria glabrata, J. Parasitol, vol.82, pp.343-347, 1996. ,
Whole genome analysis of a schistosomiasis-transmitting freshwater snail, Nat. Commun, vol.8, p.15451, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01523953
A family of variable immunoglobulin and lectin domain containing molecules in the snail Biomphalaria glabrata, Dev. Comp. Immunol, vol.48, pp.234-243, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01082870
A Shift from Cellular to Humoral Responses Contributes to Innate Immune Memory in the Vector Snail Biomphalaria glabrata, PLoS Pathog, vol.12, p.1005361, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01259482
20 years of the SMART protein domain annotation resource, Nucleic Acids Res, vol.46, pp.493-496, 2018. ,
, Recent updates, new developments and status in 2015, vol.43, pp.257-260, 2015.
GUIDANCE: A web server for assessing alignment confidence scores, Nucleic Acids Res, vol.38, pp.23-28, 2010. ,
A general empirical model of protein evolution derived from multiple protein families using a maximum-likelihood approach, Mol. Biol. Evol, vol.18, pp.691-699, 2001. ,
Molecular Evolutionary Genetics Analysis across Computing Platforms, Mol. Biol. Evol, vol.35, pp.1547-1549, 2018. ,
The alpha-macroglobulin bait region. Sequence diversity and localization of cleavage sites for proteinases in five mammalian alpha-macroglobulins, J. Biol. Chem, vol.264, pp.15781-15789, 1989. ,
The NTR module: Domains of netrins, secreted frizzled related proteins, and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases, Protein Sci, vol.8, pp.1636-1642, 1999. ,
Human complement component C3: cDNA coding sequence and derived primary structure, Proc. Natl. Acad. Sci, vol.82, pp.708-712, 1985. ,
Amino acid sequence of guinea pig C3a anaphylatoxin, Protein Seq. Data Anal, vol.1, pp.473-478, 1988. ,
Characterization of CD109. In Graduate Department of Medical Biophysics, 2011. ,
The internal thioester and the covalent binding properties of the complement proteins C3 and C4, Protein Sci, vol.6, pp.263-274, 1997. ,
The covalent binding reaction of complement component C3, J. Immunol, vol.161, pp.985-990, 1998. ,
Multiple forms of alpha-2 macroglobulin in shrimp Fenneropenaeus chinesis and their transcriptional response to WSSV or Vibrio pathogen infection, Dev. Comp. Immunol, vol.34, pp.677-684, 2010. ,
The genome sequence of Drosophila melanogaster, Science, vol.287, pp.2185-2195, 2000. ,
The genome sequence of the malaria mosquito Anopheles gambiae, Science, vol.298, pp.129-149, 2002. ,
Comparative Functional Study of Thioester-containing Related Proteins in the Recently Sequenced Genome of Biomphalaria glabrata, Iran. J. Parasitol, vol.13, pp.79-88, 2018. ,
Identification and characterization of TEP family genes in Yesso scallop (Patinopecten yessoensis) and their diverse expression patterns in response to bacterial infection, Fish Shellfish Immunol, vol.79, pp.327-339, 2018. ,
Thioester-containing proteins in the tsetse fly (Glossina) and their response to trypanosome infection, Insect Mol. Biol, vol.27, pp.414-428, 2018. ,
Amino acid sequence of hen ovomacroglobulin (ovostatin) deduced from cloned cDNA, DNA Seq, vol.5, pp.111-119, 1994. ,
Ovostatin: A novel proteinase inhibitor from chicken egg white. II. Mechanism of inhibition studied with collagenase and thermolysin, J. Biol. Chem, vol.258, pp.7490-7498, 1983. ,
Conserved Role of a Complement-like Protein in Phagocytosis Revealed by dsRNA Knockout in Cultured Cells of the Mosquito, Anopheles gambiae, Cell, vol.104, pp.709-718, 2001. ,
The transmembrane protein Macroglobulin complement-related is essential for septate junction formation and epithelial barrier function in Drosophila, Development, vol.141, pp.899-908, 2014. ,
Complement-Related Regulates Autophagy in Neighboring Cells, Cell, vol.170, pp.158-171, 2017. ,
Thioester-Containing Proteins 2 and 4 Affect the Metabolic Activity and Inflammation Response in Drosophila, Infect. Immun, vol.86, pp.810-827, 2018. ,
A New Role of the Mosquito Complement-like Cascade in Male Fertility in Anopheles gambiae, PLoS Biol, vol.13, p.1002255, 2015. ,
URL : https://hal.archives-ouvertes.fr/inserm-02135240
Identification and expression of gene transcripts generated during an anti-parasitic response in Biomphalaria glabrata, Dev. Comp. Immunol, vol.31, pp.657-671, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00170685
Cell surface antigen CD109 is a novel member of the alpha(2) macroglobulin/C3, C4, C5 family of thioester-containing proteins, Blood, vol.99, pp.1683-1691, 2002. ,
Identification of CD109 as part of the TGF-beta receptor system in human keratinocytes, FASEB J, vol.20, pp.1525-1527, 2006. ,
Up-regulation of CD109 expression is associated with carcinogenesis of the squamous epithelium of the oral cavity, Cancer Sci, vol.99, pp.1916-1923, 2008. ,
CD109 deficiency induces osteopenia with an osteoporosis-like phenotype in vivo, Genes Cells, vol.23, pp.590-598, 2018. ,
CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro, Sci. Rep, vol.9, p.16317, 2019. ,
Understanding the role of host hemocytes in a squid/vibrio symbiosis using transcriptomics and proteomics, Front. Immunol, vol.3, p.91, 2012. ,
Macrophage complement receptors and pathogen clearance, Cell. Microbiol, vol.9, pp.2095-2102, 2007. ,
Structural insights on complement activation, FEBS J, vol.282, pp.3883-3891, 2015. ,
Anopheles gambiae TEP1 forms a complex with the coiled-coil domain of LRIM1/APL1C following a conformational change in the thioester domain, PLoS ONE, vol.14, p.218203, 2019. ,
The genomic structure, alternative splicing and immune response of Chlamys farreri thioester-containing protein, Dev. Comp. Immunol, vol.33, pp.1070-1076, 2009. ,