Epidemiological profile and north–south gradient driving baseline systemic involvement of primary Sjögren’s syndrome

Pilar Brito-Zerón (1) , Nihan Acar-Denizli (2) , Wan-Fai Ng (3) , Ildiko Fanny Horvath (4) , Astrid Rasmussen (5) , Raphaèle Seror (6) , Xiaomei Li (7) , Chiara Baldini (8) , Jacques-Eric Gottenberg (9) , Debashish Danda (10) , Luca Quartuccio (11) , Roberta Priori (12) , Gabriela Hernandez-Molina (13) , Berkan Armagan (14) , Aike Kruize (15) , Seung-Ki Kwok (16) , Marika Kvarnström (17) , Sonja Praprotnik (18) , Damien Sene (19) , Roberto Gerli (20) , Roser Solans (21) , Maureen Rischmueller (22) , Thomas Mandl (23) , Yasunori Suzuki (24) , David Isenberg (25) , Valeria Valim (26) , Piotr Wiland (27) , Gunnel Nordmark (28) , Guadalupe Fraile (29) , Hendrika Bootsma (30) , Hideki Nakamura (31) , Roberto Giacomelli (32) , Valérie Devauchelle-Pensec (33, 34) , Benedikt Hofauer (35) , Michele Bombardieri (36) , Virginia Fernandes Moça Trevisani (37) , Daniel Hammenfors (38) , Sandra Pasoto (39) , Soledad Retamozo (40) , Tamer Gheita (41) , Fabiola Atzeni (42) , Jacques Morel (43, 44) , Cristina Vollenweider (45) , Margit Zeher (46) , Kathy Sivils (5) , Bei Xu (7) , Stefano Bombardieri (8) , Pulukool Sandhya (47) , Salvatore de Vita (48) , Antonina Minniti (49) , Jorge Sánchez-Guerrero (50) , Levent Kilic (51) , Eefje van Der Heijden (15) , Sung-Hwan Park (16) , Marie Wahren-Herlenius (17) , Xavier Mariette (52) , Manuel Ramos-Casals (53)

1 IDIBAPS - Hospital Clinic
2 Mimar Sinan Üniversitesi
3 Institute of Cellular Medicine [Newcastle]
4 University of Debrecen [Hungary]
5 OMRF - Oklahoma Medical Research Foundation
6 Rheumatology Department - CHU Le Kremlin-Bicêtre
7 Anhui Provincial Hospital - Departement of Rheumatology and Immunology, Hefei
8 Rheum Unit - PISA - Rheumatology Unit
9 Service de rhumatologie [Strasbourg]
10 Christian Medical College & Hospital - Department of Clinical Immunology and Rheumatology, Vellore
11 DSMB - Rheumatology Clinic, Udine
12 UO Complessa Reumatologia, Rome
13 Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán - National Institute of Medical Science and Nutrition Salvador Zubiran [Mexico]
14 Rheumatology, Hacettepe University Faculty of Medicine, Ankara
15 University Medical Center [Utrecht]
16 Department of Internal Medicine - Division of Rheumatology, Seoul
17 Department of Medicine - Unit of Experimental Rheumatology, Stockhom
18 University Medical Center
19 Hôpital Lariboisière
20 University and Azienda Ospedaliera of Perugia,
21 Vall d'Hebron University Hospital [Barcelona]
22 The Queen Elizabeth Hospital, Adelaide
23 Department of Rheumatology, Skane University Hospital
24 Division of Rheumatology Kanazawa University Graduate School of Medicine, Kanazawa
25 Centre for Rheumatology - London
26 Department of Medicine, Universidade Federal do Espirito Santo, Vitoria
27 Wrocław Medical University
28 Uppsala University
29 Hospital Universitario Ramón y Cajal [Madrid]
30 University of Groningen [Groningen]
31 Department of Immunology and Rheumatology, Nagasaki, Japan
32 UNIVAQ - University of L'Aquila [Italy]
33 LBAI - Lymphocytes B, Autoimmunité et Immunothérapies
34 CHU - BREST - Rhumato - CHRU Brest - Service de Rhumatologie
35 University of Freiburg [Freiburg]
36 Queen Mary University London
37 Unifesp - Federal University of Sao Paulo
38 UiB - University of Bergen
39 HCFMUSP - Rheumatology Division, Hospital das Clinicas, Sao Paulo
40 Universidad de Córdoba = University of Córdoba [Córdoba]
41 Rheumatology Department, Cairo
42 Messina and Milan Univ, Milan
43 Département de Rhumatologie[Montpellier]
44 IGMM - Institut de Génétique Moléculaire de Montpellier
45 Rheumatology, Buenos Aires
46 Department of Immunology [Debrecen, Hungary]
47 Clinical Immunology & Rheumatology, Vellore
48 Department of Medical Area, University Hospital Santa Maria della Misericordia, Udine
49 Physics Department,Rome University "LaSapienza" - Physics Department,Rome University "LaSapienza"
50 Department of Immunology [Mexico City]
51 Rheumatology, Hacetttepe University Faculty of Medicine, Ankara
52 GHU Paris-Sud - Laboratoire d'Immunologie [AP-HP Hôpital Kremlin-Bicêtre]
53 CELLEX-IDIBAPS Department of Autoimmune Diseases, Barcelona

To characterize the systemic phenotype of primary Sjögren's syndrome at diagnosis by analysing the EULAR-SS disease activity index (ESSDAI) scores.

Mots clés: gender; phenotype; primary Sjögren’s syndrome; geoepidemiology; ethnicity

Domaines: Sciences du Vivant [q-bio]; Immunologie

Pilar Brito-Zerón, Nihan Acar-Denizli, Wan-Fai Ng, Ildiko Fanny Horvath, Astrid Rasmussen, et al.. Epidemiological profile and north–south gradient driving baseline systemic involvement of primary Sjögren’s syndrome. Rheumatology, 2019, ⟨10.1093/rheumatology/kez578⟩. ⟨hal-02425545⟩