Quantitative analysis of the Brucella suis proteome reveals metabolic adaptation to long-term nutrient starvation

Sascha Al Dahouk (1) , Véronique Jubier-Maurin (2) , Heinrich Neubauer (3) , Stephan Köhler (2)

1 Department of Biological Safety
2 IRIM - Institut de Recherche en Infectiologie de Montpellier
3 Friedrich-Loeffler-Institute, German National Reference Centre for Human and Animal Brucellosis, Jena, Germany

During the infection process, bacteria are confronted with various stress factors including nutrient starvation. In an in vitro model, adaptation strategies of nutrient-starved brucellae, which are facultative intracellular pathogens capable of long-term persistence, were determined.

Domaines: Sciences du Vivant [q-bio]; Microbiologie et Parasitologie; Bactériologie

Sascha Al Dahouk, Véronique Jubier-Maurin, Heinrich Neubauer, Stephan Köhler. Quantitative analysis of the Brucella suis proteome reveals metabolic adaptation to long-term nutrient starvation. BMC Microbiology, 2013, 13 (1), pp.199. ⟨10.1186/1471-2180-13-199⟩. ⟨hal-02425088⟩