Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study

François Dépret 1, 2 Clement Hoffmann 3 Laura Daoud 4 Camille Thieffry 5 Laure Monplaisir 6 Jules Creveaux 7 Djillali Annane 8, 9 Erika Parmentier 5 Daniel Mathieu 10 Sandrine Wiramus 11, 12 Dominique Demeure Dit Latte 13, 14 Aubin Kpodji 15 Julien Textoris 16 Florian Robin 17 Kada Klouche 18, 19 Emmanuel Pontis 20 Guillaume Schnell 21 François Barbier 22 Jean-Michel Constantin 23 Thomas Clavier Damien Du Cheyron 24 Nicolas Terzi 25 Bertrand Sauneuf 26 Emmanuel Guérot 27 Thomas Lafon 28 Alexandre Herbland 29 Bruno Megarbane 30 Thomas Leclerc 31 Vincent Mallet 32 Romain Pirracchio 33 Matthieu Legrand 34
Abstract : The use of hydroxocobalamin has long been advocated for treating suspected cyanide poisoning after smoke inhalation. Intravenous hydroxocobalamin has however been shown to cause oxalate nephropathy in a single-center study. The impact of hydroxocobalamin on the risk of acute kidney injury (AKI) and survival after smoke inhalation in a multicenter setting remains unexplored.
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Submitted on : Sunday, December 29, 2019 - 10:45:08 AM
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François Dépret, Clement Hoffmann, Laura Daoud, Camille Thieffry, Laure Monplaisir, et al.. Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study. Critical Care, BioMed Central, 2019, 23 (1), pp.421. ⟨10.1186/s13054-019-2706-0⟩. ⟨hal-02424961⟩

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