Genomic architecture and introgression shape a butterfly radiation

Nathaniel B Edelman , Paul B Frandsen , Michael Miyagi , Bernardo Clavijo (1) , John Davey , Rebecca B Dikow (2) , Gonzalo García-Accinelli , Steven M van Belleghem , Nick Patterson (3) , Daniel E Neafsey (3) , Richard Challis , Sujai Kumar , Gilson Moreira , R P Gilson , Camilo Salazar , Mathieu Chouteau (4) , Brian A Counterman , Riccardo Papa , Mark Blaxter (5) , Robert Reed (6) , Kanchon K Dasmahapatra , Marcus Kronforst , Mathieu Joron (7) , Chris D Jiggins , W. Owen Owen Mcmillan , Federica Di Palma (3) , Andrew J Blumberg , John Wakeley (8) , David Jaffe (9) , James Mallet (10)

1 TGAC - The Genome Analysis Centre
2 Smithsonian Institution
3 BROAD INSTITUTE - Broad Institute of MIT and Harvard
4 LEEISA - Laboratoire Ecologie, Evolution, Interactions des Systèmes amazoniens
5 Institute of Evolutionary Biology
6 Invasive Species Branch
7 CEFE - Centre d’Ecologie Fonctionnelle et Evolutive
8 Harvard University
9 Broad Institute [Cambridge]
10 OEB - Department of Organismic and Evolutionary Biology [Cambridge]

We used 20 de novo genome assemblies to probe the speciation history and architecture of gene flow in rapidly radiating Heliconius butterflies. Our tests to distinguish incomplete lineage sorting from introgression indicate that gene flow has obscured several ancient phylogenetic relationships in this group over large swathes of the genome. Introgressed loci are underrepresented in low-recombination and gene-rich regions, consistent with the purging of foreign alleles more tightly linked to incompatibility loci. Here, we identify a hitherto unknown inversion that traps a color pattern switch locus. We infer that this inversion was transferred between lineages by introgression and is convergent with a similar rearrangement in another part of the genus. These multiple de novo genome sequences enable improved understanding of the importance of introgression and selective processes in adaptive radiation.

Domaines: Sciences du Vivant [q-bio]; Biodiversité; Evolution [q-bio.PE]

Nathaniel B Edelman, Paul B Frandsen, Michael Miyagi, Bernardo Clavijo, John Davey, et al.. Genomic architecture and introgression shape a butterfly radiation. Science, 2019, 366 (6465), pp.594-599. ⟨10.1126/science.aaw2090⟩. ⟨hal-02395414⟩