Global Tuberculosis Control, 2011. ,
Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair, Embo J, vol.22, issue.23, pp.6408-6418, 2003. ,
Structural and biochemical analysis of sliding clamp/ligand interactions suggest a competition between replicative and translesion DNA polymerases, J Mol Biol, vol.335, issue.5, pp.1187-1197, 2004. ,
URL : https://hal.archives-ouvertes.fr/hal-00188922
Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp, Proc Natl Acad Sci, issue.105, pp.11116-11121, 2008. ,
Structure-based design of short peptide ligands binding onto the E. coli processivity ring, J Med Chem, vol.54, issue.13, pp.4627-4637, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00604997
Binding inhibitors of the bacterial sliding clamp by design, J Med Chem, vol.54, issue.13, pp.4831-4838, 2011. ,
Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins, vol.348, pp.1106-1112, 2015. ,
Structural and thermodynamic dissection of linear motif recognition by the E. coli sliding clamp, J Med Chem, vol.56, issue.21, pp.8665-8673, 2013. ,
Discovery of Lead Compounds Targeting the Bacterial Sliding Clamp Using a Fragment-Based Approach, J Med Chem, 2014. ,
Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp, Cell, vol.69, issue.3, pp.425-437, 1992. ,
Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli, J Biol Chem, vol.256, issue.2, pp.976-983, 1981. ,
The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity, EMBO Rep, vol.1, issue.6, pp.484-488, 2000. ,
Pivotal role of the beta-clamp in translesion DNA synthesis and mutagenesis in E. coli cells, DNA Repair (Amst), issue.9, pp.703-708, 2001. ,
The processivity factor beta controls DNA polymerase IV traffic during spontaneous mutagenesis and translesion synthesis in vivo, EMBO Rep, vol.3, issue.1, pp.45-49, 2002. ,
Interaction of the beta sliding clamp with MutS, ligase, and DNA polymerase I, Proc Natl Acad Sci U S A, vol.98, issue.15, pp.8376-8380, 2001. ,
A universal protein-protein interaction motif in the eubacterial DNA replication and repair systems, Proc Natl Acad Sci, vol.98, issue.20, pp.11627-11632, 2001. ,
Structural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the beta-clamp, Embo J, vol.22, issue.21, pp.5883-5892, 2003. ,
Differential modes of peptide binding onto replicative sliding clamps from various bacterial origins, J Med Chem, vol.57, issue.18, pp.7565-7576, 2014. ,
Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs, J Med Chem, vol.58, issue.11, pp.4693-4702, 2015. ,
kinITC: a new method for obtaining joint thermodynamic and kinetic data by isothermal titration calorimetry, J Am Chem Soc, vol.134, issue.1, pp.559-565, 2012. ,
PRIGo: a new multi-axis goniometer for macromolecular crystallography, J Synchrotron Radiat, vol.22, issue.4, pp.895-900, 2015. ,
Data processing and analysis with the autoPROC toolbox, Acta Crystallogr D Biol Crystallogr, vol.67, pp.293-302, 2011. ,
, , 2017.
MOLREP: an automated program for molecular replacement, J. Appl. Cryst, vol.30, pp.1022-1025, 1997. ,
PHENIX: a comprehensive Python-based system for macromolecular structure solution, Acta Cryst, vol.66, pp.213-221, 2010. ,
Overview of the CCP4 suite and current developments, Acta. Cryst, vol.67, pp.235-242, 2011. ,
Structure of the SSB-DNA polymerase III interface and its role in DNA replication, Embo J, vol.30, issue.20, pp.4236-4247, 2011. ,
Scalable molecular dynamics with NAMD, Journal of Computationnal Chemistry, vol.26, issue.16, pp.1781-1802, 2005. ,
Free energy via molecular simulation: applications to chemical and biomolecular systems, Annu Rev Biophys Biophys Chem, vol.18, pp.431-492, 1989. ,
Good practices in free-energy calculations, J Phys Chem B, issue.32, pp.10235-10253, 2010. ,
All-atom empirical potential for molecular modeling and dynamics studies of proteins, J Phys Chem B, vol.102, pp.3586-3616, 1998. ,
Joining Thermodynamics and kinetics by kinITC, Methods in Enzymology ,
Foundations and contemporary approaches, vol.567, pp.281-300, 2016. ,
Coupling of local folding to site-specific binding of proteins to DNA, Science, vol.263, issue.5148, pp.777-784, 1994. ,
Contribution to the thermodynamics of protein folding from the reduction in water-accessible nonpolar surface area, Biochemistry, vol.30, issue.17, pp.4237-4244, 1991. ,
Heat capacity changes and hydrophobic interactions in the binding of FK506 and rapamycin to the FK506 binding protein, Proc Natl Acad Sci, vol.89, issue.11, pp.4781-4785, 1992. ,
A bipartite polymerase-processivity factor interaction: only the internal beta binding site of the alpha subunit is required for processive replication by the DNA polymerase III holoenzyme, J Mol Biol, vol.350, issue.2, pp.228-239, 2005. ,
The DNA replication machine of a gram-positive organism, J Biol Chem, vol.275, issue.37, pp.28971-28983, 2000. ,