, , p.1
Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons 2 demonstrates its major role in nociception, EMBO J, vol.24, pp.315-324, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00016908
A G protein is 4 involved in the angiotensin AT2 receptor inhibition of the T-type calcium current in non-5 differentiated NG108-15 cells, J Biol Chem, vol.270, pp.1670-1674, 1995. ,
A limited arthritic model for chronic pain 7 studies in the rat, Pain, pp.73-81, 1992. ,
, , p.9
Impaired nociception and pain sensation in mice lacking the capsaicin receptor, Science, vol.288, pp.306-319, 2000. ,
Chemical determinants involved in anandamide-induced 12 inhibition of T-type calcium channels, J Biol Chem, vol.282, pp.2314-2323, 2007. ,
, , p.14
Abnormal coronary function in mice 15 deficient in alpha1H T-type Ca2+ channels, Science, vol.302, pp.1416-1418, 2003. ,
, , p.17
, Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced 18 chronic muscle pain, J Neurosci, pp.10360-10368, 2010.
Attenuated 20 pain responses in mice lacking Ca(V)3.2 T-type channels, Genes Brain Behav, vol.6, pp.425-431, 2007. ,
Calcium-dependent inhibition of T-22 type calcium channels by TRPV1 activation in rat sensory neurons, Pflugers Arch, vol.462, pp.709-722, 2011. ,
5-HT receptor subtypes involved in the 24 spinal antinociceptive effect of acetaminophen in rats, Eur J Pharmacol, pp.1-7, 2001. ,
Acetaminophen prevents 26 hyperalgesia in central pain cascade, Neurosci Lett, pp.50-53, 2008. ,
The local antinociceptive effects of paracetamol in 28 neuropathic pain are mediated by cannabinoid receptors, Eur J Pharmacol, pp.214-219, 2007. ,
Modulation of native T-type calcium channels by omega-3 30 fatty acids, Biochem. Biophys. Res Commun, vol.327, pp.485-493, 2005. ,
Isolation and structure of a brain constituent that binds to the 33 cannabinoid receptor, Science, vol.258, pp.1946-1949, 1992. ,
Improved superfusion 1 technique for rapid cooling or heating of cultured cells under patch-clamp conditions, J Neurosci, vol.151, issue.2, pp.178-185, 2006. ,
Systemic paracetamol-induced 4 analgesic and antihyperalgesic effects through activation of descending serotonergic pathways 5 involving spinal 5-HT? receptors, Eur J Pharmacol, vol.677, pp.93-101, 2012. ,
, , p.7
State-dependent properties of a new T-type calcium channel blocker 8 enhance Ca(V)3.2 selectivity and support analgesic effects, Pain, vol.154, pp.283-293, 2013. ,
, , p.10
Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 11 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system, J Biol, vol.12, pp.31405-31412, 2005. ,
, , vol.14
Identification of a new class of 15 molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain, J Biol 16 Chem, vol.276, pp.42639-42644, 2001. ,
Regulation of CA(v)3.2 Ca2+ channel activity by protein 18 tyrosine phosphorylation, J Microbiol Biotechnol, vol.18, pp.365-368, 2008. ,
20 Regulation of T-type calcium channels by Rho-associated kinase, Nat Neurosci, vol.10, pp.854-860, 2007. ,
Adrenaline enhances odorant contrast by modulating signal 22 encoding in olfactory receptor cells, Nat Neurosci, vol.2, pp.133-138, 1999. ,
Lack of the burst firing 24 of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G), p.25 ,
, Ca(2+) channels, Neuron, vol.31, pp.35-45, 2001.
Lack of delta waves and sleep disturbances during non-rapid eye 27 movement sleep in mice lacking alpha1G-subunit of T-type calcium channels, Proc Natl Acad Sci USA, vol.28, pp.18195-18199, 2004. ,
Antinociception by systemically-administered acetaminophen 30 (paracetamol) involves spinal serotonin 5-HT(7) and adenosine A(1) receptors, as well as peripheral 31 adenosine A(1) receptors, Neurosci Lett, 2013. ,
,
, Hyperalgesia induced by spinal and peripheral hydrogen sulfide: evidence for involvement of Cav3.2 34 T-type calcium channels, Pain, vol.142, pp.127-132, 2009.
36 TRPV1 in brain is involved in acetaminophen-induced antinociception, PLoS ONE, 2010. ,
,
, Endocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesia, Pain, vol.2, pp.190-200, 2008.
The efficacy of locally applied aspirin and 4 acetaminophen in postoperative pain after third molar surgery, Clin Pharmacol Ther, vol.52, pp.292-297, 1992. ,
Three types of neuronal calcium channel with different 7 calcium agonist sensitivity, Nature, vol.316, pp.440-443, 1985. ,
Kawabata 9 A. Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 10 and TRPA1 channels in mice, Br J Pharmacol, vol.166, pp.1738-1743, 2012. ,
, , p.12
Inhibition of T-type calcium channels and hydrogen sulfide-13 forming enzyme reverses paclitaxel-evoked neuropathic hyperalgesia in rats, Neuroscience, vol.14, pp.148-156, 2011. ,
Role of TRPV1 receptors in descending modulation of pain, Mol 16 Cell Endocrino, pp.79-83, 2008. ,
URL : https://hal.archives-ouvertes.fr/hal-00531985
Paracetamol 18 exerts a spinal antinociceptive effect involving an indirect interaction with 5-hydroxytryptamine3 19 receptors: in vivo and in vitro evidence, J Pharmacol Exp Ther, pp.8-14, 1996. ,
Molecular physiology of low-voltage-activated t-type calcium channels, 21 Physiol Rev, vol.83, pp.117-161, 2003. ,
Role of endocannabinoids and endovanilloids in Ca2+ signalling, Cell Calcium, vol.45, issue.23, pp.611-624, 2009. ,
Acetaminophen reinforces 25 descending inhibitory pain pathways, Clin Pharmacol Ther, vol.84, pp.47-51, 2008. ,
Analgesic effect of 27 acetaminophen in humans: first evidence of a central serotonergic mechanism, Clin Pharmacol Ther, vol.28, pp.371-379, 2006. ,
, , p.30
, , p.31
Pyridyl amides as potent inhibitors of T-type calcium 32 channels, Bioorg. Med Chem Lett, vol.21, pp.1692-1696, 2011. ,
A second endogenous cannabinoid that modulates long-34 term potentiation, Nature, vol.388, pp.773-778, 1997. ,
Antagonism of T-type calcium 13 channels inhibits high-fat diet-induced weight gain in mice, J Clin Invest, pp.1659-67, 2009. ,
Neuromedin U 15 inhibits T-type Ca2+ channel currents and decreases membrane excitability in small dorsal root 16 ganglia neurons in mice, Cell Calcium, vol.49, pp.12-22, 2011. ,
Alpha-cobratoxin inhibits T-type 18 calcium currents through muscarinic M4 receptor and G?-protein ?? subunits-dependent protein 19 kinase A pathway in dorsal root ganglion neurons, Neuropharmacology, vol.62, pp.1062-1072, 2012. ,
Modulation of low-voltage-activated T-type Ca(2+) 21 channels, Biochim Biophys Acta, vol.1828, pp.1550-1559, 2013. ,
The anandamide transport 23 inhibitor AM404 activates vanilloid receptors, Eur J Pharmacol, vol.396, pp.39-42, 2000. ,