Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer

Eve Combès (1) , Augusto Andrade , Diego Tosi , Henri-Alexandre Michaud (1) , Flavie Coquel (2) , Véronique Garambois (1) , Delphine Desigaud , Marta Jarlier (1) , Arnaud Coquelle (1) , Philippe Pasero (2) , Nathalie Bonnefoy (3) , Jérôme Moreaux (4) , Pierre Martineau (1) , Maguy Md del Rio (5) , Roderick Beijersbergen , Nadia Vezzio-Vie (1) , Celine Gongora (1)

1 IRCM - U1194 Inserm - UM - Institut de Recherche en Cancérologie de Montpellier
2 IGH - Institut de génétique humaine
3 CGM - Centre de génétique moléculaire
4 IRB - Institut de recherche en biothérapie
5 IRIM - Institut de Recherche en Infectiologie de Montpellier

Domaines: Sciences du Vivant [q-bio]; Cancer

Eve Combès, Augusto Andrade, Diego Tosi, Henri-Alexandre Michaud, Flavie Coquel, et al.. Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer. Cancer Research, 2019, 79 (11), pp.2933-2946. ⟨10.1158/0008-5472.CAN-18-2807⟩. ⟨hal-02361669⟩