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, Ligue Contre le Cancer Comité du Gard (AA), Odysseus grant G.0029.12 from Research Foundation Flanders (FWO, to PT), grants from the National Institutes of Health USA RO1 NS083372, RO1 NS037402 and RO1 GM077875 (JMH), and from the CZ, We acknowledge financial support from the Foundation ARC (AA)

. Afbir1, Amino acid sequence of the single BIR domain region of human Survivin is aligned using ClustalW with each of the two BIR domains in BIR1 of Aspergillus fumigatus. Disruption of either Phe86 or Val89 (red frames, Survivin inhibits S12 binding

, Asterisks mark residues forming the interface between Survivin dimers