Comment on “Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death”

Abstract : Shlezinger et al (Reports, 8 September 2017, p. 1037) report that the common fungus Aspergillus fumigatus, a cause of aspergillosis, undergoes caspase-dependent apoptosis-like cell death triggered by lung neutrophils. However, the technologies they used do not provide reliable evidence that fungal cells die via a protease signaling cascade thwarted by a fungal caspase inhibitor homologous to human survivin.
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Submitted on : Friday, November 8, 2019 - 11:05:47 AM
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Abdel Aouacheria, Kyle Cunningham, J. Marie Hardwick, Zdena Palková, Ted Powers, et al.. Comment on “Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death”. Science, American Association for the Advancement of Science, 2018, 360 (6395), pp.eaar6910. ⟨10.1126/science.aar6910⟩. ⟨hal-02355307⟩

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