The ongoing challenge of latent tuberculosis, Philos Trans R Soc Lond B Biol Sci, vol.369, 2014. ,
The global burden of latent tuberculosis infection: A re-estimation using mathematical modelling, PLoS Med, vol.13, p.1002152, 2016. ,
, Global tuberculosis report, WHO, 2018.
The incubation period distribution of tuberculosis estimated with a molecular epidemiological approach, Int J Epidemiol, vol.40, pp.964-970, 2011. ,
Familial Susceptibility to Tuberculosis: Its Importance as a Public Health Problem, 1944. ,
Genetics of human susceptibility to active and latent tuberculosis: Present knowledge and future perspectives, Lancet Infect Dis, vol.18, pp.64-75, 2018. ,
Twin studies on the significance of genetic factors in tuberculosis, Am Rev Tuberc, vol.47, pp.549-571, 1943. ,
Twin research from the time of Francis Galton to the presentday, Proc R Soc Lond B Biol Sci, vol.128, pp.62-81, 1939. ,
Discussion on the influence of heredity on disease, with special reference to tuberculosis, cancer, and diseases of the nervous system: Introductory address, Proc R Soc Med, vol.2, pp.54-60, 1909. ,
Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency, Science, vol.280, pp.1432-1435, 1998. ,
Inherited interleukin 12 deficiency in a child with bacille Calmette-Guérin and Salmonella enteritidis disseminated infection, J Clin Invest, vol.102, pp.2035-2040, 1998. ,
Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients, Science, vol.280, pp.1435-1438, 1998. ,
Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guérin infection, N Engl J Med, vol.335, pp.1956-1961, 1996. ,
A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection, N Engl J Med, vol.335, pp.1941-1949, 1996. ,
Mendelian susceptibility to mycobacterial disease: Genetic, immunological, and clinical features of inborn errors of IFN-? immunity, Semin Immunol, vol.26, pp.454-470, 2014. ,
Human interferon-gamma-mediated immunity is a genetically controlled continuous trait that determines the outcome of mycobacterial invasion, Immunol Rev, vol.178, pp.129-137, 2000. ,
Interleukin-12 receptor beta1 deficiency in a patient with abdominal tuberculosis, J Infect Dis, vol.184, pp.231-236, 2001. ,
IL-12R?1 deficiency in two of fifty children with severe tuberculosis from Iran, Morocco, and Turkey, PLoS One, vol.6, p.18524, 2011. ,
Inherited and acquired immunodeficiencies underlying tuberculosis in childhood, Immunol Rev, vol.264, pp.103-120, 2015. ,
Clinical tuberculosis in 2 of 3 siblings with interleukin-12 receptor beta1 deficiency, Clin Infect Dis, vol.37, pp.302-306, 2003. ,
Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome, J Exp Med, vol.212, pp.1641-1662, 2015. ,
Interleukin-12 receptor beta 1 chain deficiency in a child with disseminated tuberculosis, Clin Infect Dis, vol.40, pp.55-58, 2005. ,
Lethal tuberculosis in a previously healthy adult with IL-12 receptor deficiency, J Clin Immunol, vol.31, pp.537-539, 2011. ,
Tuberculosis and impaired IL-23-dependent IFN-? immunity in humans homozygous for a common TYK2 missense variant, Sci Immunol, vol.3, p.8714, 2018. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02070591
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity, Sci Transl Med, vol.8, pp.363-149, 2016. ,
Human IFN-? immunity to mycobacteria is governed by both IL-12 and IL-23, Sci Immunol, vol.3, p.6759, 2018. ,
The UK Biobank resource with deep phenotyping and genomic data, Nature, vol.562, pp.203-209, 2018. ,
Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage, Proc Natl Acad Sci, vol.113, pp.6713-6718, 2016. ,
,
, Accuracy of patient self-report of stroke: A systematic review from the UK Biobank stroke outcomes group, PLoS One, vol.10, p.137538, 2015.
Trends in tuberculosis in the UK, Thorax, vol.73, pp.702-703, 2018. ,
Rate of latent tuberculosis infection detected by occupational health screening of nurses new to a London teaching hospital, Infect Control Hosp Epidemiol, vol.30, pp.581-584, 2009. ,
Investigating the prevalence of latent Tuberculosis infection in a UK remand prison, J Public Health, 2019. ,
, Tuberculosis in England. Available at, 2017.
A sex-stratified genome-wide association study of tuberculosis using a multi-ethnic genotyping array, Front Genet, vol.9, p.678, 2019. ,
Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese, Nat Commun, vol.9, p.4072, 2018. ,
Discovery of susceptibility loci associated with tuberculosis in Han Chinese, Hum Mol Genet, vol.26, pp.4752-4763, 2017. ,
A locus at 5q33.3 confers resistance to tuberculosis in highly susceptible individuals, Am J Hum Genet, vol.98, pp.514-524, 2016. ,
HLA class II sequence variants influence tuberculosis risk in populations of European ancestry, Nat Genet, vol.48, pp.318-322, 2016. ,
A genome-wide association study of pulmonary tuberculosis in Morocco, Hum Genet, vol.135, pp.299-307, 2016. ,
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration, Nat Genet, vol.47, pp.523-527, 2015. ,
Genome-wide association study of ancestry-specific TB risk in the South African coloured population, Hum Mol Genet, vol.23, pp.796-809, 2014. ,
Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis, J Hum Genet, vol.57, pp.363-367, 2012. ,
A genome wide association study of pulmonary tuberculosis susceptibility in Indonesians, BMC Med Genet, vol.13, p.5, 2012. ,
Common variants at 11p13 are associated with susceptibility to tuberculosis, Nat Genet, vol.44, pp.257-259, 2012. ,
African TB Genetics Consortium; Wellcome Trust Case Control Consortium (2010) Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11, Nat Genet, vol.42, issue.2, pp.739-741 ,
Progression of recent Mycobacterium tuberculosis exposure to active tuberculosis is a highly heritable complex trait driven by 3q23 in Peruvians, 2018. ,
An atlas of genetic associations in UK Biobank, Nat Genet, vol.50, pp.1593-1599, 2018. ,
TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on nonautoimmune complex traits, PLoS One, vol.10, p.122271, 2015. ,
, International Genetics of Ankylosing Spondylitis Consortium
, TASC
, Groupe Française d'Etude Génétique des Spondylarthrites (GFEGS)
, Spondyloarthritis Research Consortium of Canada (SPARCC
, Wellcome Trust Case Control Consortium 2 (WTCCC2) (2013) Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci, Nat Genet, vol.45, pp.730-738
, International Multiple Sclerosis Genetics Consortium (IMSGC
, Wellcome Trust Case Control Consortium 2 (WTCCC2); International IBD Genetics Consortium (IIBDGC) (2013) Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis, Nat Genet, vol.45, pp.1353-1360
International IBD Genetics Consortium (IIBDGC) (2012) Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease, Nature, vol.491, pp.119-124 ,
, Collaborative Association Study of Psoriasis
, Genetic Analysis of Psoriasis Consortium; Psoriasis Association Genetics Extension; Wellcome Trust Case Control Consortium 2 (2012) Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity, Nat Genet, vol.44, pp.1341-1348
Primary immunodeficiencies and inflammatory disease: A growing genetic intersection, Trends Immunol, vol.37, pp.126-140, 2016. ,
Genetics of infectious and inflammatory diseases: Overlapping discoveries from association and exome-sequencing studies, Annu Rev Immunol, vol.35, pp.1-30, 2017. ,
Translational and clinical advances in JAK-STAT biology: The present and future of jakinibs, J Leukoc Biol, vol.104, pp.499-514, 2018. ,
Selective Tyk2 inhibitors as potential therapeutic agents: A patent review, Expert Opin Ther Pat, vol.29, pp.137-149, 2015. ,
Phase 2 trial of selective tyrosine kinase 2 inhibition in psoriasis, N Engl J Med, vol.379, pp.1313-1321, 2018. ,
Anti-TNF treatment and tuberculosis, Austin J Pulm Respir Med, vol.4, p.1055, 2017. ,
, The White Plague: Tuberculosis, Man, and Society, 1987.
The Industrial Revolution and the decline in death rates from tuberculosis, Int J Tuberc Lung Dis, vol.19, pp.502-503, 2015. ,
The Beaker phenomenon and the genomic transformation of northwest Europe, Nature, vol.555, pp.190-196, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02006656
Low penetrance, broad resistance, and favorable outcome of interleukin 12 receptor ?1 deficiency: Medical and immunological implications, J Exp Med, vol.197, pp.527-535, 2003. ,
Immunotherapy of mycobacterial infections, Semin Respir Infect, vol.16, pp.47-59, 2001. ,
Totally drug-resistant tuberculosis in India, Clin Infect Dis, vol.54, pp.579-581, 2012. ,
Management of multidrug-resistant tuberculosis, Semin Respir Crit Care Med, vol.39, pp.310-324, 2018. ,
The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis, Lancet Respir Med, issue.17, pp.30079-30085, 2017. ,
Human genetic basis of interindividual variability in the course of infection, Proc Natl Acad Sci, vol.112, pp.7118-7127, 2015. ,
Severe infectious diseases of childhood as monogenic inborn errors of immunity, Proc Natl Acad Sci, vol.112, pp.7128-7137, 2015. ,
Simple genetics for a complex disease, Genetics, vol.340, pp.689-690, 2013. ,
Distilling pathophysiology from complex disease genetics, Cell, vol.155, pp.21-26, 2013. ,
The inherited basis of diabetes mellitus: Implications for the genetic analysis of complex traits, Annu Rev Genomics Hum Genet, vol.4, pp.257-291, 2003. ,
The continuum of causality in human genetic disorders, Genome Biol, vol.17, p.233, 2016. ,
The impact of host genetic variation on infection with HIV-1, Nat Immunol, vol.16, pp.577-583, 2015. ,
Genetic heterogeneity in human disease, Cell, vol.141, pp.210-217, 2010. ,
Genetic dissection of immunity to mycobacteria: The human model, Annu Rev Immunol, vol.20, pp.581-620, 2002. ,
Genetic dissection of human blood pressure variation: Common pathways from rare phenotypes, Harvey Lect, vol.100, pp.71-101, 2004. ,