The viral F-box protein P0 induces an ER-derived autophagy degradation pathway for the clearance of membrane-bound AGO1.

Abstract : expression. Accordingly, ATI1 and ATI2 deficiency causes a significant increase in posttranscriptional gene silencing (PTGS) activity. Collectively, we identify ATI1 and ATI2 as components of an ER-associated AGO1 turnover and proper PTGS maintenance and further show how the VSR P0 manipulates this pathway.
Document type :
Journal articles
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-02349952
Contributor : Archive Ouverte Prodinra <>
Submitted on : Tuesday, November 5, 2019 - 8:11:13 PM
Last modification on : Thursday, November 7, 2019 - 1:22:56 AM

Links full text

Identifiers

Citation

Simon Michaeli, Marion Clavel, Esther Lechner, Corrado Viotti, Jian Wu, et al.. The viral F-box protein P0 induces an ER-derived autophagy degradation pathway for the clearance of membrane-bound AGO1.. Proceedings of the National Academy of Sciences of the United States of America, 2019, ⟨10.1073/pnas.1912222116⟩. ⟨hal-02349952⟩

Share

Metrics

Record views

12