Molecular portraits of human breast tumours, Nature, vol.406, pp.747-752, 2000. ,
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications, Proc. Natl. Acad. Sci, vol.98, pp.10869-10874, 2001. ,
Radiotherapy in triple-negative breast cancer: Current situation and upcoming strategies, Crit. Rev. Oncol. Hematol, vol.131, pp.96-101, 2018. ,
EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells, Nat. Commun, vol.8, 2017. ,
, Cell, vol.166, pp.21-45, 2016.
Therapeutic Potential of a Novel ?v?3 Antagonist to Hamper the Aggressiveness of Mesenchymal Triple Negative Breast Cancer Sub-Type, Cancers, vol.11, p.139, 2019. ,
Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFR? Aptamer, vol.7, pp.3595-3607, 2017. ,
Non-coding RNA: What is functional and what is junk? Front, Genet, vol.6, issue.2, 2015. ,
Long Noncoding RNAs: Past, Present, and Future, Genetics, vol.193, pp.651-669, 2013. ,
Long Noncoding RNA Discovery in Cardiovascular Disease: Decoding Form to Function, Circ. Res, vol.122, pp.155-166, 2018. ,
Long Non-Coding RNA in Cancer, Int. J. Mol. Sci, vol.14, pp.4655-4669, 2013. ,
lncRNA NEAT1 is closely related with progression of breast cancer via promoting proliferation and EMT, Eur. Rev. Med. Pharmacol. Sci, vol.21, pp.1020-1026, 2017. ,
Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer, J. Transl. Med, vol.13, p.131, 2015. ,
Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotides, Nucleic Acids Res, vol.37, pp.4518-4531, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-02127334
Characterization of BCAR4, a novel oncogene causing endocrine resistance in human breast cancer cells, J. Cell. Physiol, vol.226, pp.1741-1749, 2011. ,
The LINK-A lncRNA Activates Normoxic HIF1? Signaling in Triple-negative Breast Cancer, Nat. Cell Biol, vol.18, pp.213-224, 2016. ,
Identification of novel long non-coding RNAs in triple-negative breast cancer, Oncotarget, vol.6, pp.21730-21739, 2015. ,
Co-expression networks revealed potential core lncRNAs in the triple-negative breast cancer, Gene, vol.591, pp.471-477, 2016. ,
LncRNAs as new biomarkers to differentiate triple negative breast cancer from non-triple negative breast cancer, Oncotarget, vol.7, pp.13047-13059, 2016. ,
A Comprehensive NGS Data Analysis of Differentially Regulated miRNAs, piRNAs, lncRNAs and sn/snoRNAs in Triple Negative Breast Cancer, J. Cancer, vol.8, pp.578-596, 2017. ,
LncRNA LET function as a tumor suppressor in breast cancer development, Eur. Rev. Med. Pharmacol. Sci, vol.22, pp.6002-6007, 2018. ,
Long non-coding RNA XIST inhibited breast cancer cell growth, migration, and invasion via miR-155/CDX1 axis, Biochem. Biophys. Res. Commun, vol.498, pp.1002-1008, 2018. ,
Long non-coding RNA-CTD-2108O9.1 represses breast cancer metastasis by influencing leukemia inhibitory factor receptor, Cancer Sci, vol.109, pp.1764-1774, 2018. ,
Long noncoding RNA GAS5 suppresses triple negative breast cancer progression through inhibition of proliferation and invasion by competitively binding miR-196a-5p, Biomed. Pharmacother, vol.104, pp.451-457, 2018. ,
Reciprocal regulation of Hsa-miR-1 and long noncoding RNA MALAT1 promotes triple-negative breast cancer development, Tumor Biol, vol.37, pp.7383-7394, 2016. ,
Long non-coding RNA MALAT1 promotes proliferation and invasion via targeting miR-129-5p in triple-negative breast cancer, Biomed. Pharmacother, vol.95, pp.922-928, 2017. ,
The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial-Mesenchymal Transition in Breast Cancer, Cancer Res, vol.76, pp.2626-2636, 2016. ,
Combined inhibition of EGFR and c-ABL suppresses the growth of triple-negative breast cancer growth through inhibition of HOTAIR, Oncotarget, vol.6, pp.11150-11161, 2015. ,
C-MYC-induced upregulation of lncRNA SNHG12 regulates cell proliferation, apoptosis and migration in triple-negative breast cancer, Am. J. Transl. Res, vol.9, pp.533-545, 2017. ,
LINC01638 lncRNA activates MTDH-Twist1 signaling by preventing SPOP-mediated c-Myc degradation in triple-negative breast cancer, Oncogene, vol.37, pp.6166-6179, 2018. ,
Adriaenssens, E. H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b, Oncotarget, vol.6, pp.29209-29223, 2015. ,
A novel long non-coding RNA linc-ZNF469-3 promotes lung metastasis through miR-574-5p-ZEB1 axis in triple negative breast cancer, Oncogene, pp.4662-4678, 2018. ,
Long non-coding RNA LINC00673 promotes breast cancer proliferation and metastasis through regulating B7-H6 and epithelial-mesenchymal transition, Am. J. Cancer Res, vol.8, pp.1273-1287, 2018. ,
Down-regulation of lncRNA-ATB inhibits epithelial-mesenchymal transition of breast cancer cells by increasing miR-141-3p expression, Biochem. Cell Biol, vol.97, pp.193-200, 2019. ,
Long Non-Coding RNA (LncRNA) HOXA11-AS Promotes Breast Cancer Invasion and Metastasis by Regulating Epithelial-Mesenchymal Transition, Med. Sci. Monit, vol.23, pp.3393-3403, 2017. ,
Long non-coding RNA OR3A4 promotes proliferation and migration in breast cancer, Biomed. Pharmacother, vol.96, pp.426-433, 2017. ,
Long non-coding RNA MIAT promotes breast cancer progression and functions as ceRNA to regulate DUSP7 expression by sponging miR-155-5p, Oncotarget, vol.8, pp.76153-76164, 2017. ,
Long non-coding RNA GHET1 promotes human breast cancer cell proliferation, invasion and migration via affecting epithelial mesenchymal transition, Cancer Biomark, vol.22, pp.565-573, 2018. ,
Long non-coding RNAs AC026904.1 and UCA1: A "one-two punch" for TGF-?-induced SNAI2 activation and epithelial-mesenchymal transition in breast cancer, Theranostics, vol.8, pp.2846-2861, 2018. ,
Long non-coding RNA NNT-AS1 affects progression of breast cancer through miR-142-3p/ZEB1 axis, Biomed. Pharmacother, vol.103, pp.939-946, 2018. ,
PVT1 affects EMT and cell proliferation and migration via regulating p21 in triple-negative breast cancer cells cultured with mature adipogenic medium, Acta Biochim. Biophys. Sin, vol.50, pp.1211-1218, 2018. ,
An androgen receptor negatively induced long non-coding RNA ARNILA binding to miR-204 promotes the invasion and metastasis of triple-negative breast cancer, Cell Death Differ, vol.25, pp.2209-2220, 2018. ,
lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6, Mol. Cancer Res, vol.13, pp.330-338, 2015. ,
Down-regulated expression of LINC00518 prevents epithelial cell growth and metastasis in breast cancer through the inhibition of CDX2 methylation and activation of the Wnt signaling pathway, Biochim. Biophys. Acta (BBA) Mol, pp.708-723 ,
Adam12 and lnc015192 act as ceRNAs in breast cancer by regulating miR-34a, Oncogene, vol.37, pp.6316-6326, 2018. ,
Sossey-Alaoui, K. miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer, Mol. Cancer, vol.11, issue.5, 2012. ,
Long Noncoding RNA snaR Regulates Proliferation, Migration and Invasion of Triple-negative Breast Cancer Cells, Anticancer Res, vol.36, pp.6289-6295, 2016. ,
Small RNAs with a big role in gene regulation, Nat. Rev. Genet, vol.5, pp.522-531, 2004. ,
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia, Proc. Natl. Acad. Sci, vol.99, pp.15524-15529, 2002. ,
BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas, J. Pathol, vol.207, pp.243-249, 2005. ,
MicroRNA Cluster 221-222 and Estrogen Receptor ? Interactions in Breast Cancer, J. Natl. Cancer Inst, vol.102, pp.706-721, 2010. ,
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation, Cancer Res, vol.65, pp.9628-9632, 2005. ,
The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms, Cancer Res, vol.68, pp.2745-2754, 2008. ,
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers, Proc. Natl. Acad. Sci, vol.101, pp.2999-3004, 2004. ,
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth, Cancer Res, vol.67, pp.8433-8438, 2007. ,
MicroRNAs: Regulators of cancer metastasis and epithelial-mesenchymal transition (EMT), Chin. J. Cancer, vol.33, pp.140-147, 2014. ,
Identification of dysregulated miRNAs in triple negative breast cancer: A meta-analysis approach, J. Cell. Physiol, vol.234, pp.11768-11779, 2018. ,
microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers, Oncotarget, vol.5, pp.1174-1184, 2014. ,
Integrative analysis of lncRNAs and miRNAs with coding RNAs associated with ceRNA crosstalk network in triple negative breast cancer, vol.10, pp.5883-5897, 2017. ,
Identification of miR-10b, miR-26a, miR-146a and miR-153 as potential triple-negative breast cancer biomarkers, Cell. Oncol, vol.38, pp.433-442, 2015. ,
MicroRNAs in the Imprinted DLK1-DIO3 Region Repress the Epithelial-to-Mesenchymal Transition by Targeting the TWIST1 Protein Signaling Network, J. Biol. Chem, vol.287, pp.42695-42707, 2012. ,
miR-200a inhibits migration of triple-negative breast cancer cells through direct repression of the EPHA2 oncogene, Carcinogenesis, vol.36, pp.1051-1060, 2015. ,
MicroRNA-200b targets protein kinase C? and suppresses triple-negative breast cancer metastasis, Carcinogenesis, vol.35, pp.2254-2263, 2014. ,
Epigenetic silencing of miR-200c in breast cancer is associated with aggressiveness and is modulated by ZEB1, Genes Chromosomes Cancer, vol.56, pp.147-158, 2017. ,
miR-30a inhibits epithelial-mesenchymal transition and metastasis in triple-negative breast cancer by targeting ROR1, Oncol. Rep, vol.39, pp.2635-2643, 2018. ,
MicroRNA-146a inhibits cell migration and invasion by targeting RhoA in breast cancer, Oncol. Rep, vol.36, pp.189-196, 2016. ,
Fang, L. miR-143-3p targeting LIM domain kinase 1 suppresses the progression of triple-negative breast cancer cells, Am. J. Transl. Res, vol.9, pp.2276-2285, 2017. ,
The microRNAs miR-200b-3p and miR-429-5p target the LIMK1/CFL1 pathway to inhibit growth and motility of breast cancer cells, Oncotarget, vol.8, pp.85276-85289, 2017. ,
miR-139-5p is a regulator of metastatic pathways in breast cancer, RNA, vol.19, pp.1767-1780, 2013. ,
MiR-212-5p Suppresses the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer by Targeting Prrx2, Cell. Physiol. Biochem, vol.44, pp.1785-1795, 2017. ,
miR-199a-5p confers tumor-suppressive role in triple-negative breast cancer, BMC Cancer, vol.16, 2016. ,
Prognostic value of microRNA-9 and microRNA-155 expression in triple-negative breast cancer, Hum. Pathol, vol.68, pp.69-78, 2017. ,
Regulation of cancerous progression and epithelial-mesenchymal transition by miR-34c-3p via modulation of MAP3K2 signaling in triple-negative breast cancer cells, Biochem. Biophys. Res. Commun, vol.483, pp.10-16, 2017. ,
miR-3178 inhibits cell proliferation and metastasis by targeting Notch1 in triple-negative breast cancer, Cell Death Dis, vol.9, 1059. ,
Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer, Oncotarget, vol.6, pp.16638-16652, 2015. ,
miR-125b inhibited epithelial-mesenchymal transition of triple-negative breast cancer by targeting MAP2K7, OncoTargets Ther, vol.9, pp.2639-2648, 2016. ,
miR-655 suppresses epithelial-to-mesenchymal transition by targeting Prrx1 in triple-negative breast cancer, J. Cell. Mol. Med, vol.20, pp.864-873, 2016. ,
MicroRNA-27a promotes tumorigenesis via targeting AKT in triple negative breast cancer, Mol. Med. Rep, vol.17, pp.562-570, 2018. ,
MicroRNA-182 promotes proliferation and metastasis by targeting FOXF2 in triple-negative breast cancer, Oncol. Lett, vol.14, pp.4805-4811, 2017. ,
Expression and regulatory function of miRNA-182 in triple-negative breast cancer cells through its targeting of profilin 1, Tumor Biol, vol.34, pp.1713-1722, 2013. ,
MicroRNA-454 may function as an oncogene via targeting AKT in triple negative breast cancer, J. Biol. Res, vol.24, 2017. ,
MiR-373 drives the epithelial-to-mesenchymal transition and metastasis via the miR-373-TXNIP-HIF1?-TWIST signaling axis in breast cancer, Oncotarget, vol.6, pp.32701-32712, 2015. ,
Targets Adiponectin Receptor 1 to Promote the Epithelial-to-Mesenchymal Transition in Breast Cancer, PLoS ONE, vol.8, 2013. ,
Critical role of miR-10b in transforming growth factor-?1-induced epithelial-mesenchymal transition in breast cancer, Cancer Gene Ther, vol.21, pp.60-67, 2014. ,
RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2, Hepatology, vol.67, pp.2254-2270, 2018. ,
Histone acetyltransferase KAT6A upregulates PI3K/AKT signaling through TRIM24 binding, Cancer Res, vol.77, pp.6190-6201, 2017. ,
Histone Modifications and Cancer, Cold Spring Harb. Perspect. Biol, vol.8, 2016. ,
Dysregulation of histone methyltransferases in breast cancer-Opportunities for new targeted therapies?, Mol. Oncol, vol.10, pp.1497-1515, 2016. ,
Histone deacetylase inhibitors suppress mutant p53 transcription via HDAC8/YY1 signals in triple negative breast cancer cells, Cell. Signal, vol.28, pp.506-515, 2016. ,
Effects of SAHA and EGCG on Growth Potentiation of Triple-Negative Breast Cancer Cells, Cancers, vol.11, 2019. ,
Overexpression of the steroidogenic acute regulatory protein in breast cancer: Regulation by histone deacetylase inhibition, Biochem. Biophys. Res. Commun, vol.509, pp.476-482, 2019. ,
Targeting triple negative breast cancer with histone deacetylase inhibitors, Expert Opin. Investig. Drugs, vol.26, pp.1199-1206, 2017. ,
Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat, Breast Cancer Res, vol.14, 2012. ,
Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model, Mol. Cancer, vol.15, 2016. ,
The synergistic effect of SAHA and parthenolide in MDA-MB231 breast cancer cells, J. Cell. Physiol, vol.230, pp.1276-1289, 2015. ,
Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation, Clin. Cancer Res, vol.14, pp.5385-5399, 2008. ,
Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes, BMC Genom, vol.19, 2018. ,
Histone H3 lysine 4 acetylation and methylation dynamics define breast cancer subtypes, Oncotarget, vol.7, pp.5094-5109, 2016. ,
Genetic alterations of histone lysine methyltransferases and their significance in breast cancer, Oncotarget, vol.6, pp.2466-2482, 2014. ,
Identification of epigenetic factors regulating the mesenchyme to epithelium transition by RNA interference screening in breast cancer cells, BMC Cancer, vol.16, 2016. ,
Epigenetic reprogramming of epithelial mesenchymal transition in triple negative breast cancer cells with DNA methyltransferase and histone deacetylase inhibitors, J. Exp. Clin. Cancer Res, vol.37, pp.1848-1857, 2018. ,
Enhanced expression of histone chaperone APLF associate with breast cancer, Mol. Cancer, vol.17, p.76, 2018. ,
TIP60 inhibits metastasis by ablating DNMT1?SNAIL2-driven epithelial-mesenchymal transition program, J. Mol. Cell Biol, vol.8, pp.384-399, 2016. ,
The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition, Oncotarget, vol.8, pp.65548-65565, 2017. ,
EZH2 promotes migration and invasion of triple-negative breast cancer cells via regulating TIMP2-MMP-2/-9 pathway, Am. J. Cancer Res, vol.8, pp.422-434, 2018. ,
Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer, Breast Cancer Res. Treat, vol.159, pp.443-456, 2016. ,
Histone Methyltransferase hSETD1A Is a Novel Regulator of Metastasis in Breast Cancer, Mol. Cancer Res, vol.13, pp.461-469, 2015. ,
Overexpression of histone demethylase JMJD5 promotes metastasis and indicates a poor prognosis in breast cancer, Int. J. Clin. Exp. Pathol, vol.8, pp.10325-10334, 2015. ,
Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448, BMC Cancer, vol.16, p.160, 2016. ,
Lysine demethylase KDM3A regulates breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53, vol.36, pp.47-59, 2017. ,
Histone deacetylase 8 triggers the migration of triple negative breast cancer cells via regulation of YAP signals, Eur. J. Pharmacol, vol.845, pp.16-23, 2018. ,
Suberoylanilide hydroxamic acid (SAHA) promotes the epithelial mesenchymal transition of triple negative breast cancer cells via HDAC8/FOXA1 signals, Biol. Chem, vol.397, pp.75-83, 2016. ,
Histone deacetylase inhibitor entinostat reverses epithelial to mesenchymal transition of breast cancer cells by reversing the repression of E-cadherin, Breast Cancer Res. Treat, vol.143, pp.99-111, 2014. ,
Histone Deacetylase Inhibitor Entinostat Inhibits Tumor-Initiating Cells in Triple-Negative Breast Cancer Cells, Mol. Cancer Ther, vol.14, pp.1848-1857, 2015. ,
Inhibition of Histone Deacetylases Reverses Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells through a Slug Mediated Mechanism, Mol. Biol, vol.52, pp.474-481, 2018. ,
Mitochondrial Apoptosis and FAK Signaling Disruption by a Novel Histone Deacetylase Inhibitor, HTPB, in Antitumor and Antimetastatic Mouse Models, PLoS ONE, vol.7, 2012. ,
Suppression of Invasion and Metastasis of Triple-Negative Breast Cancer Lines by Pharmacological or Genetic Inhibition of Slug Activity, Neoplasia, vol.16, pp.1047-1058, 2014. ,
UNC0638, a G9a inhibitor, suppresses epithelial-mesenchymal transition-mediated cellular migration and invasion in triple negative breast cancer, Mol. Med. Rep, vol.17, 2018. ,
Epigenetics and human disease, Int. J. Biochem. Cell Biol, vol.41, pp.136-146, 2009. ,
CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future, Oncogene, vol.21, pp.5427-5440, 2002. ,
CpG island methylator phenotype of multigene in serum of sporadic breast carcinoma, Tumor Biol, vol.31, pp.321-331, 2010. ,
Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value, Nat. Commun, vol.6, p.5899, 2015. ,
,
DNA methylation profile of triple negative breast cancer-specific genes comparing lymph node positive patients to lymph node negative patients ,
Expression of epithelial-mesenchymal transition-related markers in triple-negative breast cancer: ZEB1 as a potential biomarker for poor clinical outcome, Hum. Pathol, vol.46, pp.1267-1274, 2015. ,
Epigenetics and MicroRNAs in Cancer, Int. J. Mol. Sci, vol.19, p.459, 2018. ,
Dysregulation of the epigenome in triple-negative breast cancers: Basal-like and claudin-low breast cancers express aberrant DNA hypermethylation, Exp. Mol. Pathol, vol.95, pp.276-287, 2013. ,
Epigenetic silencing of CREB3L1 by DNA methylation is associated with high-grade metastatic breast cancers with poor prognosis and is prevalent in triple negative breast cancers, Breast Cancer Res, vol.18, 2016. ,
Down-regulation of BRMS1 by DNA hypermethylation and its association with metastatic progression in triple-negative breast cancer, Int. J. Clin. Exp. Pathol, vol.8, pp.11076-11083, 2015. ,
DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells, Oncotarget, vol.7, pp.70924-70935, 2016. ,
The EZH2-H3K27me3-DNMT1 complex orchestrates epigenetic silencing of the wwc1 gene, a Hippo/YAP pathway upstream effector, in breast cancer epithelial cells, Cell. Signal, vol.51, pp.243-256, 2018. ,
Epigenetic silencing of ADAMTS18 promotes cell migration and invasion of breast cancer through AKT and NF-?B signaling, vol.6, pp.1399-1408, 2017. ,
The dual role of FOXF2 in regulation of DNA replication and the epithelial-mesenchymal transition in breast cancer progression, Cell. Signal, vol.28, pp.1502-1519, 2016. ,
Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/?-catenin signaling and is frequently methylated in breast cancer, Oncotarget, vol.8, pp.39443-39459, 2017. ,