Leisure-time vigorous physical activity is associated with better lung function: the prospective ECRHS study

Elaine Fuertes , Anne-Elie Carsin (1) , Josep M. Antó , Roberto Bono , Angelo Guido Corsico , Pascal Demoly (2, 3, 4, 5) , Thorarinn Gislason , José-Antonio Gullón , Christer Janson , Deborah Jarvis , Joachim Heinrich , Mathias Holm , Bénédicte Leynaert (6) , Alessandro Marcon (7) , Jesús Martinez-Moratalla , Dennis Nowak , Silvia Pascual Erquicia , Nicole M. Probst-Hensch , Chantal Raherison (8) , Wasif Raza , Francisco Gómez Real , Melissa Russell , José Luis Sánchez-Ramos , Joost Weyler , Judith Garcia Aymerich

1 CIBERESP - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública = Consortium for Biomedical Research of Epidemiology and Public Health
2 CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier]
3 Service d'allergologie et de pneumologie [Hôpital Arnaud de Villeneuve]
4 iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique
5 SU - Sorbonne Université
6 PHERE (UMR_S_1152 / U1152) - Physiopathologie et Epidémiologie des Maladies Respiratoires
7 UNIVR | DDSP - Department of Diagnostics and Public Health [Verona]
8 EPICENE - Cancer environnement

OBJECTIVE: We assessed associations between physical activity and lung function, and its decline, in the prospective population-based European Community Respiratory Health Survey cohort. METHODS: FEV1 and FVC were measured in 3912 participants at 27-57 years and 39-67 years (mean time between examinations=11.1 years). Physical activity frequency and duration were assessed using questionnaires and used to identify active individuals (physical activity >=2 times and >=1 hour per week) at each examination. Adjusted mixed linear regression models assessed associations of regular physical activity with FEV1 and FVC. RESULTS: Physical activity frequency and duration increased over the study period. In adjusted models, active individuals at the first examination had higher FEV1 (43.6 mL (95% CI 12.0 to 75.1)) and FVC (53.9 mL (95% CI 17.8 to 89.9)) at both examinations than their non-active counterparts. These associations appeared restricted to current smokers. In the whole population, FEV1 and FVC were higher among those who changed from inactive to active during the follow-up (38.0 mL (95% CI 15.8 to 60.3) and 54.2 mL (95% CI 25.1 to 83.3), respectively) and who were consistently active, compared with those consistently non-active. No associations were found for lung function decline. CONCLUSION: Leisure-time vigorous physical activity was associated with higher FEV1 and FVC over a 10-year period among current smokers, but not with FEV1 and FVC decline.

Mots clés: Humans; Female; Male; Sensitivity and Specificity; Adult; Aged; Middle Aged; Surveys and Questionnaires; Europe; Lung Diseases; Prospective Studies; Predictive Value of Tests; Exercise; Forced Expiratory Volume; Lung; Vital Capacity; adults; cohort; forced expiratory volume in one second; forced vital capacity; Leisure Activities; physical activity; smoking

Domaines: Sciences du Vivant [q-bio]

Elaine Fuertes, Anne-Elie Carsin, Josep M. Antó, Roberto Bono, Angelo Guido Corsico, et al.. Leisure-time vigorous physical activity is associated with better lung function: the prospective ECRHS study. Thorax, 2018, 73 (4), pp.376--384. ⟨10.1136/thoraxjnl-2017-210947⟩. ⟨hal-02348856⟩