C), 63.2 (d, 3 J CF = 26.1 Hz), CDCl 3 ): ? = 156.9, vol.1, p.31 ,
CDCl 3 ): ? = -117.5 (d, 3 J HF = 38.2 Hz) ppm. HMRS (ESI): calcd. for C 15 H 27 FNO ,
, Compound 15 (66 mg, 90 %, Z/E = 91:9) was obtained, in accordance with procedure 1A, from sulfone 8f (100 mg, 0.28 mmol), freshly distilled furfuraldehyde (?L, 0.34 mmol) and NaHMDS (1.0 m in THF, 42 ?L, 42 mmol)
, CDCl 3 ): ? = 157.6 (d, 1 J CF = 260, vol.128
3 (d, 2 J CF = 25.8 Hz), vol.63, pp.29-37 ,
CDCl 3 ): ? = -117.2 (dt, 3 J H F = 36.9 Hz) ppm. HMRS (ESI): calcd. for C 16 H 21 FNO, vol.23 ,
22) was obtained, in accordance with procedure 1A, from sulfone 8f (100 mg, 0.28 mmol), 4-benzyloxybutanal (58 ?L, 0.34 mmol) and NaHMDS (1.0 m in THF, 42 ?L, 42 mmol), CDCl 3 ): ? = 7.28-7.24 (m, 5 H), vol.78 ,
CDCl 3 ): ? = 157.3 (d, 1 J CF = ,
, , vol.128, p.127
, , vol.76
C), 29.5 (d, 4 J CF = 1.6 Hz), vol.46, pp.20-23 ,
Hz) ppm. 19 F NMR (376 MHz ,
HMRS (ESI): calcd. for C 19 H 27 FNO 2 ,
39) was obtained, in accordance with procedure 1B, from sulfone 8f (100 mg, 0.28 mmol), N,N-dibenzyluracil-5-carbaldehyde (108 mg, 0.34 mmol) and NaHMDS (1.0 m in THF, 42 ?L, 42 mmol) ,
(m, 4 H) ppm. 13 C NMR (100 MHz ,
d, 4 J CF = 3.6 Hz), 99.0 (d, 3 J CF = 6.5 Hz), 76.6 (d, 3 J CF = 7.1 Hz, 2 C, C), vol.128, p.127 ,
, , 2193.
, C) ppm. 19 F NMR (376 Hz, CDCl 3 ): ? = -118.1 (br. s, 1 F) ppm. HRMS (ESI): calcd. for C 16 H 26 FN 2 O 3, Compound 18 (141 mg, 64 %) was obtained, in accordance with procedure 1A, from oxetane 8f (250 mg, vol.1, pp.3121-3128, 1927.
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