Fluorescent Phosphorus Dendrimers: Towards Material and Biological Applications

Jieru Qiu (1, 2) , Aurélien Hameau (1) , Xiangyang Shi (2) , Serge Mignani (3, 4) , Jean Pierre Majoral (1) , Anne-Marie Caminade (1)

1 LCC - Laboratoire de chimie de coordination
2 CCEB - College of Chemistry, Chemical Engineering and Biotechnology, Donghua University
3 LCBPT - UMR 8601 - Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques
4 Centro de Química da Madeira

Fluorescent derivatives of phosphorhydrazone dendrimers are reviewed. Diverse types of fluorophores have been used, such as pyrene, naphthol, anthracene, dansyl, diketone, phthalocyanine, maleimide, julolidine, rhodamine, fluorescein, or fluorene derivatives. The fluorescent groups can be located either as terminal groups on the surface, at the core, linked to the core (off-center), or to the branches of the dendritic structure. After fundamental research on their synthesis, these compounds have been used in the fields of catalysis, nanomaterials, OLEDs, sensors and biology/nanomedicine, in particular for monitoring transfection, or for their anti-inflammatory or anti-cancer properties.

Mots clés: Biology; Dendrimers; Fluorescence; Nanostructures; Synthesis design

Domaines: Chimie de coordination

Jieru Qiu, Aurélien Hameau, Xiangyang Shi, Serge Mignani, Jean Pierre Majoral, et al.. Fluorescent Phosphorus Dendrimers: Towards Material and Biological Applications. ChemPlusChem, 2019, 84 (8), pp.1070-1080. ⟨10.1002/cplu.201900337⟩. ⟨hal-02335059⟩