Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation

Amy O’connell , Maxim Gerashchenko , Marie-Françoise O'Donohue , Samantha Rosen , Eric Huntzinger (1) , Diane Gleeson , Antonella Galli (2) , Edward Ryder (2) , Siqi Cao , Quinn Murphy , Shideh Kazerounian , Sarah Morton , Klaus Schmitz-Abe , Vadim Gladyshev , Pierre-Emmanuel Gleizes (3) , Bertrand Séraphin (4) , Pankaj Agrawal (5)

1 ARN - Architecture et réactivité de l'ARN
2 The Wellcome Trust Sanger Institute [Cambridge]
3 LBME - Laboratoire de biologie moléculaire eucaryote
4 IGBMC - Institut de génétique et biologie moléculaire et cellulaire
5 Institute of Physics

Domaines: Biochimie, Biologie Moléculaire; Biologie cellulaire

Amy O’connell, Maxim Gerashchenko, Marie-Françoise O'Donohue, Samantha Rosen, Eric Huntzinger, et al.. Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation. PLoS Genetics, 2019, 15 (2), pp.e1007917. ⟨10.1371/journal.pgen.1007917⟩. ⟨hal-02327840⟩