, Papers of particular interest, published within the period of review, have been highlighted as: of special interest of outstanding interest

N. Festuccia, I. Gonzalez, N. Owens, and P. Navarro, Mitotic bookmarking in development and stem cells, vol.144, pp.3633-3645, 2017.
URL : https://hal.archives-ouvertes.fr/pasteur-02024822

F. Zenk, Germ line-inherited H3K27me3 restricts enhancer function during maternal-to-zygotic transition, Science, vol.80, pp.212-216, 2017.

M. E. Oomen and J. Dekker, Epigenetic characteristics of the mitotic chromosome in 1D and 3D, Crit Rev Biochem Mol Biol, vol.52, pp.185-204, 2017.

A. Piunti and A. Shilatifard, Epigenetic balance of gene expression by polycomb and compass families, Science, vol.80, p.352, 2016.

I. J. De-castro, E. Gokhan, and P. Vagnarelli, Resetting a functional G1 nucleus after mitosis, Chromosoma, vol.125, pp.607-619, 2016.

T. Nagano, Cell-cycle dynamics of chromosomal organization at single-cell resolution, Nature, vol.547, pp.61-67, 2017.

J. Dufourt, Temporal control of transcription by Zelda in living Drosophila embryos, 2018.

T. Ferraro, Transcriptional memory in the Drosophila embryo, Curr Biol, vol.26, pp.212-218, 2016.
URL : https://hal.archives-ouvertes.fr/hal-02187328

, Using MS2-MCP system in the early Drosophila embryo, the authors visualized transcriptional memory for the first time in a living multicellular embryo

D. Hnisz, K. Shrinivas, R. A. Young, A. K. Chakraborty, and P. A. Sharp, A phase separation model for transcriptional control, Cell, vol.169, pp.13-23, 2017.

A. R. Strom, Phase separation drives heterochromatin domain formation, Nature, vol.547, pp.241-245, 2017.

J. B. Woodruff, The centrosome is a selective condensate that nucleates microtubules by concentrating tubulin, pp.169-1066, 2017.

B. Schuettengruber, H. M. Bourbon, D. Croce, L. Cavalli, and G. , Genome regulation by polycomb and trithorax: 70 years and counting, Cell, vol.171, pp.34-57, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01596016

S. Petruk, TrxG and PcG proteins but not methylated histones remain associated with DNA through replication, Cell, vol.150, pp.922-933, 2012.

K. L. Black, Chromatin proteins and RNA are associated with DNA during all phases of mitosis, Cell Discov, vol.2, 2016.

E. Hörmanseder, H3K4 methylation-dependent memory of somatic cell identity inhibits reprogramming and development of nuclear transfer embryos, Cell Stem Cell, vol.21, pp.135-143, 2017.

P. A. Steffen, Quantitative in vivo analysis of chromatin binding of polycomb and trithorax group proteins reveals retention of ASH1 on mitotic chromatin, Nucleic Acids Res, vol.41, pp.5235-5250, 2013.

, Using time-lapse microscopy on living EGFP tagged Ash1 transgenic Drosophila embryos, the authors showed that Ash1 decorates mitotic chromosomes. Moreover, they employed quantitative imaging methods to reveal that Ash1 binds to chromatin dynamically

G. A. Blobel, A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit, Mol Cell, vol.36, pp.970-983, 2009.

, This paper was among the firsts to show that mitotic binding by MLL at specific loci accelerates their post-mitotic transcriptional reactivation

H. Zhang, MLL1 inhibition reprograms epiblast stem cells to naive pluripotency, Cell Stem Cell, vol.18, pp.481-494, 2016.

R. Toyama, M. L. Rebbert, A. Dey, K. Ozato, and I. B. Dawid, Brd4 associates with mitotic chromosomes throughout early zebrafish embryogenesis, Dev Dynam, vol.237, pp.1636-1644, 2008.

B. N. Devaiah, A. Gegonne, and D. S. Singer, Bromodomain 4: a cellular Swiss army knife, J Leukoc Biol, vol.100, pp.679-686, 2016.

R. Zhao, T. Nakamura, Y. Fu, Z. Lazar, and D. L. Spector, Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation, Nat Cell Biol, vol.13, pp.1295-1304, 2011.

, This paper demonstrated the consequences of mitotic bookmarking (by BRD4 and H4K5 acetylation) on post-mitotic transcriptional dynamics in mammalian cells

K. C. Palozola, Mitotic transcription and waves of gene reactivation during mitotic exit. Science (80, vol.358, pp.119-122, 2017.

S. S. Teves, A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes, p.257451, 2018.

S. C. Sun, TBP dynamics during mouse oocyte meiotic maturation and early embryo development, PLoS One, vol.8, pp.1-6, 2013.

M. Raccaud and D. M. Suter, Transcription factor retention on mitotic chromosomes: regulatory mechanisms and impact on cell fate decisions, FEBS Lett, vol.592, pp.878-887, 2017.

N. Festuccia, Mitotic binding of Esrrb marks key regulatory regions of the pluripotency network, Nat Cell Biol, vol.18, pp.1139-1148, 2016.
URL : https://hal.archives-ouvertes.fr/pasteur-01972743

, By using live imaging and ChIP experiments in ES cells, this paper identified Essrb as a potential mitotic bookmarker. A subset of interphase-bound targets, remain bound by Essrb during mitosis and correspond to key regulatory regions

Y. Liu, Widespread mitotic bookmarking by histone marks and transcription factors in pluripotent stem cells, Cell Rep, vol.19, pp.1283-1293, 2017.

S. S. Teves, This paper demonstrated that the majority of transcription factors examined remain associated to mitotic chromosomes in ES cells. A quantitative study on Sox2 revealed that this pluripotency factor exhibits a dynamic mode of mitotic binding. This paper points to the artifactual mitotic eviction of some transcription factors triggered by formaldehyde fixation, vol.5, 2016.

C. Pallier, Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes, Mol Biol Cell, vol.14, pp.2372-2384, 2003.

A. Soufi, Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming, Cell, vol.161, pp.555-568, 2015.

M. Iwafuchi-doi and K. S. Zaret, Cell fate control by pioneer transcription factors, Development, vol.143, pp.1833-1837, 2016.

R. B. Deal, J. G. Henikoff, and S. Henikoff, Genome-wide kinetics of nucleosome. Science (80-.), vol.328, pp.1161-1165, 2010.

F. Mueller, T. J. Stasevich, D. Mazza, and J. G. Mcnally, Quantifying transcription factor kinetics: at work or at play?, Crit Rev Biochem Mol Biol, vol.48, pp.492-514, 2013.

C. Deluz, A role for mitotic bookmarking of SOX2 in pluripotency and differentiation, Genes Dev, vol.30, pp.2538-2550, 2016.

, profiled the mitotic binding for Sox2 and Oct4 and quantified their binding dynamics with quantitative imaging methods. By analyzing the consequences of Sox2 mitotic depletion

J. M. Caravaca, Bookmarking by specific and nonspecific binding of FoxA1 pioneer factor to mitotic chromosomes, Genes Dev, vol.27, pp.251-260, 2013.

, This study identified two modes of mitotic bookmarking for the pioneer factor FoxA: via sequence specific binding and via nonspecific binding

T. Muramoto, I. Müller, G. Thomas, A. Melvin, and J. R. Chubb, Methylation of H3K4 is required for inheritance of active transcriptional states, Curr Biol, vol.20, pp.397-406, 2010.

, This paper was the first to directly visualize the inheritance of transcriptionally active states down cell lineages in Dictyostelium. By using various genetic mutants, the authors demonstrated that this memory can be partially attributed to H3K4 methylation

S. Kadauke, Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1, Cell, vol.150, pp.725-737, 2012.

E. Bertrand, Localization of ASH1 mRNA particles in living yeast, Mol Cell, vol.2, pp.437-445, 1998.

T. Lionnet and R. H. Singer, Transcription goes digital, EMBO Rep, vol.13, pp.313-321, 2012.

D. Forster, Hydrodynamic fluctuations, broken symmetry, and correlation functions. (Frontiers in Physics 47, XIX, 326 S, 1975.

E. Herrera-delgado, R. Perez-carrasco, J. Briscoe, and P. Sollich, Memory functions reveal structural properties of gene regulatory networks, PLoS Comput Biol, p.14, 2018.

S. Karlin and H. E. Taylor, A first course in stochastic processes

L. Bentovim, T. T. Harden, and A. H. Depace, Transcriptional precision and accuracy in development: from measurements to models and mechanisms, vol.144, pp.3855-3866, 2017.

J. R. Chubb, Gene regulation: stable noise, vol.26, pp.61-64, 2016.

M. Lagha, XPaused Pol II coordinates tissue morphogenesis in the drosophila embryo, Cell, vol.153, pp.976-987, 2013.

C. S. Simon, A. Hadjantonakis, and C. Schröter, Making lineage decisions with biological noise: lessons from the early mouse embryo, Wiley Interdiscip Rev Dev Biol, vol.319, 2018.

J. P. Skene and S. Henikoff, CUT& RUN: targeted in situ genomewide profiling with high efficiency for low cell numbers, vol.2017, pp.1-28

L. Bintu, Dynamics of epigenetic regulation at the single cell level, vol.351, pp.720-724, 2016.

A. Huang, C. Amourda, S. Zhang, N. S. Tolwinski, and T. E. Saunders, Decoding temporal interpretation of the morphogen bicoid in the early drosophila embryo, p.6, 2017.

J. Lerner, Human mutations affect the epigenetic/bookmarking function of HNF1B, Nucleic Acids Res, vol.44, pp.8097-8111, 2016.
URL : https://hal.archives-ouvertes.fr/inserm-01361850