GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation

Marjorie Damian (1) , Véronique Pons (2) , Pedro Renault (1) , Céline M’kadmi (1) , Bartholomé Delort (1) , Lucie Hartmann (3) , Ali Kaya (4) , Maxime Louet (1) , Didier Gagne (1) , Khoubaib Ben Haj Salah (1) , Séverine Denoyelle (1) , Gilles Ferry (5) , Jean A. Boutin (5) , Renaud Wagner (3) , Jean-Alain Fehrentz (1) , Jean Martinez (1) , Jacky Marie (1) , Nicolas Floquet (1) , Céline Galés (2) , Sophie Mary (1) , Heidi Hamm (4) , Jean-Louis Banères (1)

1 IBMM - Institut des Biomolécules Max Mousseron [Pôle Chimie Balard]
2 I2MC - Institut des Maladies Métaboliques et Cardiovasculaires
3 BSC - Biotechnologie et signalisation cellulaire
4 Vanderbilt University Medical Center [Nashville]
5 IRS - Institut de Recherches SERVIER

Domaines: Biologie structurale [q-bio.BM]; Biologie moléculaire; Biophysique

Marjorie Damian, Véronique Pons, Pedro Renault, Céline M’kadmi, Bartholomé Delort, et al.. GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation. Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (17), pp.4501-4506. ⟨10.1073/pnas.1712725115⟩. ⟨hal-02322168⟩