Stem-Loop Structures within mRNA Coding Sequences Activate Translation Initiation and Mediate Control by Small Regulatory RNAs

Jonathan Jagodnik (1) , Claude Chiaruttini (2) , Maude Guillier (2)

1 EGM (UMR_8261 / FRE_3630) - Expression Génétique Microbienne
2 REGCM - Régulation de l'expression génétique chez les microorganismes

Graphical Abstract Highlights d A stem-loop within E. coli fepA mRNA coding region activates translation initiation d A similar activating stem-loop structure exists within bamA mRNA coding region d These stem-loops activate translation independently of their nucleotide sequence d Small RNAs repress fepA expression by targeting its activating structure

Domaines: Biologie moléculaire

Jonathan Jagodnik, Claude Chiaruttini, Maude Guillier. Stem-Loop Structures within mRNA Coding Sequences Activate Translation Initiation and Mediate Control by Small Regulatory RNAs. Molecular Cell, 2017, 68 (1), pp.158-170.e3. ⟨10.1016/j.molcel.2017.08.015⟩. ⟨hal-02321962⟩